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AB15664

Sigma-Aldrich

Anti-NUDEL Antibody

serum, Chemicon®

Synonym(s):

NDEL1, NudE nuclear distribution gene E homolog (A. nidulans)-like 1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

General description

NudE nuclear distribution gene E homolog (A. nidulans)-like 1 (NUDEL), also known as NDEL1, is a human gene. This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. This protein plays a role in nervous system development and is linked to LIS-1, the disease gene for a form of lissencephaly, a disorder of cortical development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specificity

Recognizes rat NUDEL

Immunogen

Synthetic Linear Peptide.

Application

Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience
This Anti-NUDEL Antibody is validated for use in WB for the detection of NUDEL.
Western Blot: 1:5000L

Quality

Routinely evaluated by immunoblot.

Target description

38 kDa

Physical form

Serum with 0.05% NaN3

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 1 year after date of receipt.

Analysis Note

Control
brain lysate

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1


Certificates of Analysis (COA)

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