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biological source
rabbit
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human, mouse
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
mouse ... Prox1(19130)
Specificity
Prox1
Immunogen
KLH-conjugated, synthetic peptide (C-QSVSPRESYRENKRKQKLPQ) corresponding to amino acids 196-215 of human prospero-related homeobox 1 (Prox1) with an N-terminal cysteine added for conjugation purposes.
Application
Detect Prox1 using this Anti-Prox1 Antibody validated for use in WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Sensory & PNS
Developmental Neuroscience
Sensory & PNS
Developmental Neuroscience
Quality
routinely evaluated by immunoblot in RIPA lysates from mouse liver cells
Target description
95kDa
Linkage
Replaces: MABE488
Physical form
0.05% sodium azide and 30% glycerol
ImmunoAffinity Purified
Storage and Stability
1 year at -20°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Description
Pricing
Storage Class Code
10-13 - German Storage Class 10 to 13
Certificates of Analysis (COA)
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Mei-Ren Pan et al.
Journal of cell science, 122(Pt 18), 3358-3364 (2009-08-27)
Prox1 is a master regulator for the development of lymphatic vasculature and the induction of lymphangiogenesis. In this study, we identified Prox1 as a new target for small ubiquitin-like modifier 1 (SUMO-1). Lysine 556 (K556) was found to be the
Estrogen receptor ? induces antiinflammatory and antitumorigenic networks in colon cancer cells.
Edvardsson, K; Strom, A; Jonsson, P; Gustafsson, J?; Williams, C
Molecular Endocrinology null
Janina Becker et al.
Nature structural & molecular biology, 20(4), 525-531 (2013-03-19)
SUMOylation is an essential modification that regulates hundreds of proteins in eukaryotic cells. Owing to its dynamic nature and low steady-state levels, endogenous SUMOylation is challenging to detect. Here, we present a method that allows efficient enrichment and identification of
Katarzyna Koltowska et al.
Development (Cambridge, England), 140(9), 1912-1918 (2013-03-22)
Tightly controlled DNA replication and RNA transcription are essential for differentiation and tissue growth in multicellular organisms. Histone chaperones, including the FACT (facilitates chromatin transcription) complex, are central for these processes and act by mediating DNA access through nucleosome reorganisation.
Cell-cell interactions influence vascular reprogramming by Prox1 during embryonic development.
Kim, H; Cruz, M; Bourdeau, A; Dumont, DJ
Testing null
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