05-773
Anti-phospho-MYPT1 (Thr850) Antibody, clone SA19, rabbit monoclonal
clone SA19, Upstate®, from rabbit
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
SA19, monoclonal
species reactivity
human, chicken
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pThr850)
Gene Information
human ... PPP1R12A(4659)
Specificity
MYPT1 phosphorylated on Thr850
Predicted to cross react with mouse and rat
Immunogen
KLH-conjugated, synthetic peptide containing the sequence ...RS[pT]GV..., in which [pT] corresponds to phosphorylated threonine at amino acid residue 850 of chicken myosin phosphatase target subunit 1 (MYPT1). Corresponds to Thr853 in human MYPT1.
Application
Anti-phospho-MYPT1 (Thr850) Antibody, clone SA19 is an antibody against phospho-MYPT1 (Thr850) for use in WB.
Research Category
Signaling
Signaling
Research Sub Category
Kinases & Phosphatases
Kinases & Phosphatases
Quality
Routinely evaluated by immunoblot on RIPA lysates from HEK293 cells phosphorylated by preincubation with ROKα/ROCK-II, active (Catalog # 14-338).
Target description
doublet at 130kDa
Physical form
Format: Purified
Protein A purified
Storage and Stability
2 years at -20°C from date of shipment
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
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Sustained therapeutic hypercapnia attenuates pulmonary arterial Rho-kinase activity and ameliorates chronic hypoxic pulmonary hypertension in juvenile rats.
Peng, G; Ivanovska, J; Kantores, C; Van Vliet, T; Engelberts, D; Kavanagh, BP; Enomoto et al.
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Role of protein phosphatase type 1 in contractile functions: myosin phosphatase.
Hartshorne, David J, et al.
The Journal of Biological Chemistry, 279, 37211-37214 (2004)
Myosin phosphatase: structure, regulation and function.
Ito, Masaaki, et al.
Molecular and Cellular Biochemistry, 259, 197-209 (2004)
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The Journal of Biological Chemistry, 277, 30614-30621 (2002)
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Lee, Dexter L, et al.
Hypertension, 44, 796-799 (2004)
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