G-020

Ganciclovir

1.0 mg/mL (1% 1M HCl in Methanol), certified reference material, Cerilliant^®

• Synonym(s): 2-Amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one, 9-(1,3-Dihydroxy-2-propoxymethyl)guanine, DHPG
• Empirical Formula (Hill Notation): C₉H₁₃N₅O₄
• CAS Number: 82410-32-0
• Molecular Weight: 255.23
• MDL number: MFCD00870588
• UNSPSC Code: 41116107
• PubChem Substance ID: 329799801

Properties

• grade: certified reference material
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 1.0 mg/mL (1% 1M HCl in Methanol)
• format: single component solution
• storage temp.: 2-8°C
• SMILES string: NC1=Nc2c(ncn2COC(CO)CO)C(=O)N1
• InChI: 1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17)
• InChI key: IRSCQMHQWWYFCW-UHFFFAOYSA-N

Description

General description

Ganciclovir is a guanine-analogue, antiviral drug indicated for the treatment of cytomegalovirus (CMV) infection and human herpesvirus 6 (HHV-6). Therapeutic drug monitoring (TDM) of ganciclovir concentrations in patient serum is performed to avoid concentration-related adverse effects such as hepatic and renal toxicity and to evaluate drug adsorption. This Certified Spiking Solution^® is suitable for use as starting materials in the preparation of calibrators, controls, or linearity standards for a variety of LC-MS/MS or GC/MS testing methods in TDM, pharmaceutical research and clinical and diagnostic testing applications.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H340,H370
• Precautionary Statements: P202 - P210 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - Muta. 1B - STOT SE 1
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup