L3307
Lumazine
97%
Synonym(s):
2,4(1H,3H)-Pteridinedione, 2,4-Dihydroxypteridine, 2,4-Pteridinediol
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About This Item
Empirical Formula (Hill Notation):
C6H4N4O2
CAS Number:
Molecular Weight:
164.12
Beilstein:
157503
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
Assay
97%
SMILES string
Oc1nc(O)c2nccnc2n1
InChI
1S/C6H4N4O2/c11-5-3-4(8-2-1-7-3)9-6(12)10-5/h1-2H,(H2,8,9,10,11,12)
InChI key
UYEUUXMDVNYCAM-UHFFFAOYSA-N
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Gerard Voerman et al.
Journal of natural products, 68(6), 938-941 (2005-06-25)
Two previously unknown lumazine derivatives, 1 and 2, have been isolated from the parasitic freshwater leech Limnatis nilotica. The structures of the compounds have been elucidated by NMR and unambiguously corroborated by chemical synthesis.
Mark Cushman et al.
The Journal of organic chemistry, 70(20), 8162-8170 (2005-11-10)
The last two steps in the biosynthesis of riboflavin, an essential metabolite that is involved in electron transport, are catalyzed by lumazine synthase and riboflavin synthase. To obtain structural probes and inhibitors of these two enzymes, two ribityllumazinediones bearing alkyl
Mark Cushman et al.
The Journal of organic chemistry, 67(20), 6871-6877 (2002-10-02)
Several analogues of a hypothetical intermediate in the reaction catalyzed by lumazine synthase were synthesized and tested as inhibitors of both Bacillus subtilis lumazine synthase and Escherichia coli riboflavin synthase. The new compounds were designed by replacement of a two-carbon
Sonia B Jiménez-Pulido et al.
Dalton transactions (Cambridge, England : 2003), 42(2), 530-541 (2012-10-23)
The oxime derived from 6-acetyl-1,3,7-trimethyllumazine (1) ((E-6-(hydroxyimino)ethyl)-1,3,7-trimethylpteridine-2,4(1H,3H)-dione, DLMAceMox) has been prepared and its molecular and crystal structure determined from spectral and XRD data. The oxime ligand was reacted with silver nitrate, perchlorate, thiocyanate, trifluoromethylsulfonate and tetrafluoroborate to give complexes with
Na'il Saleh et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 68(3), 728-733 (2007-03-31)
6-Thienyllumazine (TLM) is synthesized as a new fluorescent sensor that is capable of indicating selectively the presence of Cd(2+) ion via a fluorescence signal. Experiment has been performed in the presence of Ni(2+), Co(2+), Cu(2+), Ag(+), Mn(2+), Hg(2+), Zn(2+), Pb(2+)
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