I3875
Indoxyl sulfate potassium salt
Synonym(s):
Potassium 3-indoxyl sulfate, Urinary indican
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About This Item
Linear Formula:
C8H6NO4SK
CAS Number:
Molecular Weight:
251.30
Beilstein:
3921324
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.
Recommended Products
Assay
> 98 %
Quality Level
mp
165 °C (dec.) (lit.)
solubility
water: soluble
storage temp.
−20°C
SMILES string
[K+].[O-]S(=O)(=O)Oc1c[nH]c2ccccc12
InChI
1S/C8H7NO4S.K/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8;/h1-5,9H,(H,10,11,12);/q;+1/p-1
InChI key
MDAWATNFDJIBBD-UHFFFAOYSA-M
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Related Categories
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Product No.
Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Hidehisa Shimizu et al.
Life sciences, 92(2), 143-148 (2012-12-04)
Intercellular adhesion molecule 1 (ICAM-1) plays an important role in adhesion of monocytes/macrophages to injured tubulointerstitial tissue. The present study aimed to determine if indoxyl sulfate, a uremic toxin, regulates renal expression of ICAM-1. The effect of indoxyl sulfate on
Tino Vollmer et al.
Scientific reports, 9(1), 14525-14525 (2019-10-12)
Identifying the key toxic players within an in-vivo toxic syndrome is crucial to develop targeted therapies. Here, we established a novel method that characterizes the effect of single substances by means of an ex-vivo incubation set-up. We found that primary
Suree Lekawanvijit et al.
Circulation research, 111(11), 1470-1483 (2012-11-10)
Cardiorenal syndrome is a condition in which a complex interrelationship between cardiac dysfunction and renal dysfunction exists. Despite advances in treatment of both cardiovascular and kidney disease, cardiorenal syndrome remains a major global health problem. Characteristic of the pathophysiology of
Indoxyl sulfate upregulates liver P-glycoprotein expression and activity through aryl hydrocarbon receptor signaling
Machado, et al.
Journal of the American Society of Nephrology, 29, 906-918 (2018)
Tetsuhiro Tanaka et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(10), 4059-4075 (2013-06-25)
Chronic hypoxia in the tubulointerstitium serves as a final common pathway in progressive renal disease. Circumstantial evidence suggests that hypoxia-inducible factor (HIF)-1 in the ischemic tubules may be functionally inhibited in a chronic kidney disease (CKD) milieu. In this study
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