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E4550

Sigma-Aldrich

Diethylene glycol monoethyl ether

≥99%

Synonym(s):

2-(2-Ethoxyethoxy)ethanol, CARBITOL™, Diethylene glycol ethyl ether, Ethyldiglycol

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About This Item

Linear Formula:
C2H5OCH2CH2OCH2CH2OH
CAS Number:
111-90-0
Molecular Weight:
134.17
Beilstein:
1736441
EC Number:
203-919-7
MDL number:
MFCD00002872
UNSPSC Code:
12352112
PubChem Substance ID:
329799059
NACRES:
NA.21

vapor density

4.63 (vs air)

vapor pressure

0.12 mmHg ( 20 °C)

Assay

≥99%

form

liquid

expl. lim.

1.2 %, 135 °F
23.5 %, 182 °F

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.427 (lit.)

bp

202 °C (lit.)

mp

-80 °C (lit.)

density

0.999 g/mL at 25 °C (lit.)

SMILES string

CCOCCOCCO

InChI

1S/C6H14O3/c1-2-8-5-6-9-4-3-7/h7H,2-6H2,1H3

InChI key

XXJWXESWEXIICW-UHFFFAOYSA-N

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Legal Information

CARBITOL is a trademark of The Dow Chemical Company or an affiliated company of Dow

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

204.8 °F - closed cup

Flash Point(C)

96 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Simona Mura et al.
Journal of drug targeting, 19(3), 189-196 (2010-05-08)
The aim of this work was to evaluate the ability of Transcutol (Trc) to produce elastic vesicles with soy lecithin (SL) and study the influence of the obtained vesicles on in vitro (trans)dermal delivery of minoxidil. To this purpose, so-called
Hyun-Jong Cho et al.
International journal of pharmaceutics, 423(2), 153-160 (2012-01-03)
To achieve rapid onset of action and improved bioavailability of udenafil, a microemulsion system was developed for its intranasal delivery. Phase behavior, particle size, transmission electron microscope (TEM) images, and the drug solubilization capacity of the microemulsion were investigated. A
Rania M Hathout et al.
Molecular pharmaceutics, 7(4), 1266-1273 (2010-06-16)
This research determined the uptake of individual components of topically applied microemulsions into the stratum corneum (SC) and assessed their molecular effects on skin barrier function. The microemulsions comprised oleic acid, Tween20, Transcutol and water. The effects of selected formulations
Bhupinder Singh et al.
Drug delivery, 18(8), 599-612 (2011-10-20)
Carvedilol, a widely prescribed cardiovascular drug for hypertension and congestive heart failure, exhibits low and variable bioavailability owing to poor absorption and extensive hepatic first-pass metabolism. The current research work, therefore, entails formulation development of liquid self-nano-emulsifying drug delivery systems
J-L Delongeas et al.
Regulatory toxicology and pharmacology : RTP, 57(2-3), 284-290 (2010-03-30)
Drug safety research is frequently faced with the challenge of the selection of appropriate vehicles for use in in vivo non-clinical safety assessment studies. Reported here are the results of blend Labrasol, Labrafil and Transcutol, [L/L/T, (4/4/2, v/v/v)], excipients used
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