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901211

Sigma-Aldrich

N-Propylacrylamide

≥98.0%, stabilized with ≤200 ppm MEHQ

Synonym(s):

N-n-Propylacrylamide, N-Propyl-2-propenamide

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About This Item

Empirical Formula (Hill Notation):
C6H11NO
CAS Number:
25999-13-7
Molecular Weight:
113.16
MDL number:
MFCD00080629
UNSPSC Code:
41105319
NACRES:
NA.23
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Assay

≥98.0%

form

liquid

color

colorless to pale yellow

storage temp.

−20°C

InChI

1S/C6H11NO/c1-3-5-7-6(8)4-2/h4H,2-3,5H2,1H3,(H,7,8)

InChI key

WDFKEEALECCKTJ-UHFFFAOYSA-N

General description

N-Propylacrylamide is an acrylate monomer used in the synthesis of poly(N-n-propylacrylamide). Similar to PNIPAM, poly(N-n-propylacrylamide) (PNnPAM) is a temperature-responsive polymer known to undergo sharp thermal phase transitions (LCST). This “smart” behaviour has led to its use in a wide variety of biomedical applications such as photonics, surface modification, and nanoparticle containers for drug uptake and release.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Solution Properties and Thermal Behavior of Poly(N-n-propylacrylamide) in Water,
Ito D and Kubota K
Macromolecules, 30, 7828-7834 (1997)
Role of Anionic Surfactants in the Synthesis of Smart Microgels Based on Different Acrylamides.
Wedel B, et al.
ACS Omega, 2, 84-84 (2017)
Takeshi Mori et al.
Langmuir : the ACS journal of surfaces and colloids, 25(1), 48-50 (2008-12-17)
Syndiotactic poly(N-n-propylacrylamide)s (PNNPAM) with various racemo (r) diad contents were synthesized, and their phase transition behaviors were studied by high-sensitivity differential scanning calorimetry and FT-IR spectroscopy. The cooperativity of the phase transition increased with the increase in the r diad
Smart Homopolymer Microgels: Influence of the Monomer Structure on the Particle Properties.
Wedel B, et al.
Polymer, 8, 162-162 (2016)
Yingzhong Li et al.
Nature communications, 11(1), 4837-4837 (2020-09-26)
ATP synthesis and thermogenesis are two critical outputs of mitochondrial respiration. How these outputs are regulated to balance the cellular requirement for energy and heat is largely unknown. Here we show that major facilitator superfamily domain containing 7C (MFSD7C) uncouples

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