71868
1-(4-Methylphenyl)piperazine
≥98.0%
Synonym(s):
1-(p-Tolyl)piperazine
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About This Item
Empirical Formula (Hill Notation):
C11H16N2
CAS Number:
Molecular Weight:
176.26
Beilstein:
139489
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
Assay
≥98.0%
form
crystals
mp
29-32 °C
SMILES string
Cc1ccc(cc1)N2CCNCC2
InChI
1S/C11H16N2/c1-10-2-4-11(5-3-10)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3
InChI key
ONEYFZXGNFNRJH-UHFFFAOYSA-N
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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V Stuettgen et al.
The AAPS journal, 22(2), 33-33 (2020-01-29)
A limiting factor for oral delivery of macromolecules is low intestinal epithelial permeability. 1-Phenylpiperazine (PPZ), 1-(4-methylphenyl) piperazine (1-4-MPPZ) and 1-methyl-4-phenylpiperazine (1-M-4-PPZ) have emerged as potential permeation enhancers (PEs) from a screen carried out by others in Caco-2 monolayers. Here, their
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