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Sigma-Aldrich

Diethoxy(3-glycidyloxypropyl)methylsilane

97%

Synonym(s):

(3-Glycidyloxypropyl)methyldiethoxysilane, [3-(2,3-Epoxypropoxy)propyl]methyldiethoxysilane

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About This Item

Empirical Formula (Hill Notation):
C11H24O4Si
CAS Number:
Molecular Weight:
248.39
Beilstein:
121965
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.23

Assay

97%

form

liquid

refractive index

n20/D 1.431 (lit.)

bp

122-126 °C/5 mmHg (lit.)

density

0.978 g/mL at 25 °C (lit.)

SMILES string

CCO[Si](C)(CCCOCC1CO1)OCC

InChI

1S/C11H24O4Si/c1-4-14-16(3,15-5-2)8-6-7-12-9-11-10-13-11/h11H,4-10H2,1-3H3

InChI key

OTARVPUIYXHRRB-UHFFFAOYSA-N

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General description

Diethoxy(3-glycidyloxypropyl)methylsilane (GPMS) is an epoxysilane which can be used as a silane coupling agent for the surface treatment of a variety of materials. These silanes can also be used as adhesion promoters by modifying the surface properties of the substrates and elastomeric materials.

Application

Coverslips coated with diethoxy(3-glycidyloxypropyl)methyl silane were used as sample holders for electrostatically holding particles for optical microscopy.{52} It may be used to introduce epoxy groups to Fe3O4SiO2 nanoparticles. {53} Self assembled monolayer (SAMs) of diethoxy(3- glycidyloxypropyl)methylsilane could be formed on the oxide layer of silicon wafer to render them siloxane functionalities.{54}
GPMS can be used in the surface modification of a variety of particles such as cellulose nanocrystals, silica nanomaterials and other silicon based substrates. It functionalizes these surfaces by attaching the epoxy-silane groups with the surface molecules.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

251.6 °F - closed cup

Flash Point(C)

122 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Colloidal Particles that Rapidly Change Shape via Elastic Instabilities.
Epstein E, et al.
Small, 11(45), 6051-6057 (2015)
Surface-modified cellulose nanocrystals for biobased epoxy nanocomposites
Yue L, et al.
Polymer, 134(45), 155-162 (2018)
Photoconjugation of molecularly imprinted polymer with magnetic nanoparticles.
Xu C, et al.
ACS Applied Materials & Interfaces, 5(11), 5208-5213 (2013)
Quantitative molecular level understanding of ethoxysilane at poly (dimethylsiloxane)/polymer interfaces
Zhang C and Chen Z
Langmuir, 29(2), 610-619 (2012)
Bong Jin Hong et al.
Nucleic acids research, 33(12), e106-e106 (2005-07-09)
We have developed new surface to ensure a proper spacing between immobilized biomolecules. While DNA microarray on this surface provided each probe DNA with ample space for hybridization with incoming target DNAs, the microarray showed enhanced discrimination efficiency for various

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