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377635

Sigma-Aldrich

Octadecyl-functionalized silica gel

200-400 mesh, extent of labeling: 20-22% loading

Synonym(s):

C18 silica gel

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About This Item

MDL number:
UNSPSC Code:
12352200
NACRES:
NA.22
Pricing and availability is not currently available.

form

powder

Quality Level

extent of labeling

20-22% loading

surface area

~550 m2/g

matrix

irregular silica particle platform

matrix active group

C18 phase

particle size

200-400 mesh

pore size

60 Å pore size

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Application

Octadecyl-functionalized silica gel is generally used as a stationary phase [1][2] for low- and medium-pressure reversed-phase liquid chromatography.[3]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Antitrypanosomatid activity of flavonoid glycosides isolated from Delphinium gracile, D. staphisagria, Consolida oliveriana and from Aconitum napellus subsp. Lusitanicum
Marin C, et al.
Phytochemistry Letters, 19(2), 196-209 (2017)
Acylated flavonol glycosides from Delphinium staphisagria
Diaz JG, et al.
Phytochemistry Letters, 1(2), 125-129 (2008)
Synthesis and characterization of polymeric C18 stationary phases for liquid chromatography
Sander LC and Wise SA
Analytical Chemistry, 56(3), 504-510 (1984)

Questions

1–5 of 5 Questions  
  1. What is the pH stability of Product 377635, Octadecyl-functionalized silica gel?

    1 answer
    1. The product is expected to be unstable when used at pH above 7.5.

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  2. What is the solubility of Product 377635, Octadecyl-functionalized silica gel?

    1 answer
    1. This product is not soluble. It can be swelled in organic solvents such as methanol or acetonitrile.

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  3. How is Product 377635, Octadecyl-functionalized silica gel, prepared?

    1 answer
    1. It is prepared by the reaction of silica gel with n-octadecyltrichlorosilane. After hydrolysis of the unreacted chloro groups, silanol groups on the silica are blocked with trimethylsilyl groups.

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  4. How can Product 377635, Octadecyl-functionalized silica gel resin be cleaned of stubborn material?

    1 answer
    1. One can usually start with 40-50% chloroform in methanol and see if that cleans the resin. If not, try increasing the chloroform content gradually until it is 100%.

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  5. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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