Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 53(8), 1277-1283 (2012-06-22)
In an ongoing effort to develop a renal tracer with pharmacokinetic properties comparable to p-aminohippurate and superior to those of both (99m)Tc-mercaptoacetyltriglycine and (131)I-o-iodohippurate ((131)I-OIH), we evaluated a new renal tricarbonyl radiotracer based on the aspartic-N-monoacetic acid (ASMA) ligand, (99m)Tc(CO)(3)(ASMA).
Renal localization of radiolabeled antibody fragments presents a problem in targeted imaging and radiotherapy. We recently reported that Fab fragments labeled with 3'-[(131)I]iodohippuryl N(epsilon)-maleoyl-l-lysine (HML) demonstrated markedly low renal radioactivity levels from early postinjection in mice. Previous studies suggested that
Urologiia (Moscow, Russia : 1999), (5)(5), 80-84 (2007-04-21)
The experiments on 45 rats and 20 rabbits were made to investigate antiischemic efficacy of alpha-tocopherol in respect of various partial functions of the kidneys compared to its antioxidant activity. It is demonstrated that administration of alpha-tocopherol prior to 30-min
We studied prospectively the perioperative changes of renal function in nine children undergoing cardiac surgery with cardiopulmonary bypass (CPB). Glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) were measured with inulin and (131)I-hippuran clearances before CPB, during hypo
Clinical journal of the American Society of Nephrology : CJASN, 4(11), 1741-1746 (2009-10-08)
Renal failure is a major complication in glycogen storage disease type I (GSD I). We studied the natural course of renal function in GSD I patients. We studied differences between patients in optimal and nonoptimal metabolic control and possible renoprotective
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.