C8772
Cholera filtrate
lyophilized powder, bacterial sialidase receptor-destroying enzyme (RDE)
Synonym(s):
Cholera Filter
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About This Item
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product name
Cholera filtrate, lyophilized powder
form
lyophilized powder
Quality Level
storage temp.
2-8°C
General description
Cholera filtrate promotes the activation of adenylate cyclase. It does not affect the activity of cyclic adenosine monophosphate (cAMP) phosphodiesterase.
Application
Cholerafiltrate has been used as a receptor destroying enzyme (RDE): inhemagglutination inhibition assay of serum samples, in microneutralizationassay of mice serum samples, in hemagglutination inhibition assay to removenon-specific inhibitors from the cell culture supernatant samples
Biochem/physiol Actions
Cholera filtrate is a bacterial sialidase receptor-destroying enzyme (RDE) and may be used as crude neuraminidase. It may also be used in serological testing for influenza.
Reconstitution
After reconstituting with 5ml sterile water, it will contain 0.01% MIT as preservative.
Other Notes
See a separate listing of neuraminidase for preparations showing higher activity.
For research use only. Not for use in diagnostic procedures.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Sens. 1
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Biulleten' eksperimental'noi biologii i meditsiny, 88(10), 414-416 (1979-10-01)
An in vitro model using homogenates of the rat intestine and liver for studying the V. Cholerae culture filtrate effect on the adenylate cyclase system is proposed. Optimal conditions for the adenylate cyclase functioning have been investigated for this model.
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