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C8772

Sigma-Aldrich

Cholera filtrate

lyophilized powder, bacterial sialidase receptor-destroying enzyme (RDE)

Synonym(s):

Cholera Filter

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.77

product name

Cholera filtrate, lyophilized powder

form

lyophilized powder

Quality Level

storage temp.

2-8°C

General description

Cholera filtrate promotes the activation of adenylate cyclase. It does not affect the activity of cyclic adenosine monophosphate (cAMP) phosphodiesterase.

Application

Cholerafiltrate has been used as a receptor destroying enzyme (RDE): inhemagglutination inhibition assay of serum samples, in microneutralizationassay of mice serum samples, in hemagglutination inhibition assay to removenon-specific inhibitors from the cell culture supernatant samples

Biochem/physiol Actions

Cholera filtrate is a bacterial sialidase receptor-destroying enzyme (RDE) and may be used as crude neuraminidase. It may also be used in serological testing for influenza.

Reconstitution

After reconstituting with 5ml sterile water, it will contain 0.01% MIT as preservative.

Other Notes

See a separate listing of neuraminidase for preparations showing higher activity.
For research use only. Not for use in diagnostic procedures.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Skin Sens. 1

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Applying valency-based immuno-selection to generate broadly cross-reactive antibodies against influenza hemagglutinins
Daniela M, et al.
Nature Communications (2024)
A Riccomi et al.
Vaccines, 12(4) (2024-04-27)
A number of studies have suggested that influenza vaccination can provide protection against COVID-19, but the underlying mechanisms that could explain this association are still unclear. In this study, the effect of the 2021/2022 seasonal influenza vaccination on the immune
Ilana Fox-Fisher et al.
eLife, 10 (2021-11-30)
Blood cell counts often fail to report on immune processes occurring in remote tissues. Here, we use immune cell type-specific methylation patterns in circulating cell-free DNA (cfDNA) for studying human immune cell dynamics. We characterized cfDNA released from specific immune
WHO Tech Rep. Serv.
WHO Expert Committee on Influenza, 64 (1953)
Yao Lu et al.
Vaccine, 38(10), 2387-2395 (2020-02-06)
The highly pathogenic avian influenza (HPAI) H5N1 viruses and their spillover into the human population pose substantial economic and public health threats. Although antiviral drugs have some effect in treating influenza infection, vaccination is still the most effective intervention to

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