94258
Eriodictyol
≥95.0% (HPLC)
Synonym(s):
3′,4′,5,7-Tetrahydroxyflavanone
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About This Item
Empirical Formula (Hill Notation):
C15H12O6
CAS Number:
Molecular Weight:
288.25
MDL number:
UNSPSC Code:
12352205
PubChem Substance ID:
NACRES:
NA.25
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Assay
≥95.0% (HPLC)
form
powder
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
SMILES string
O=C1C2=C(O)C=C(O)C=C2OC(C3=CC=C(O)C(O)=C3)C1
InChI
1S/C15H12O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-5,13,16-19H,6H2
InChI key
SBHXYTNGIZCORC-UHFFFAOYSA-N
Related Categories
General description
Eriodictyolis a bitter-masking dietary flavonoid primarily extracted from yerba Santa Clause (Eriodictyon californicum) and Dracocephalum rupestre, but also present in many other citrus fruits, medicinal plants, and vegetables.
Application
Eriodictyolmay has been used to study its mechanism on IgE/Ag-induced type I hypersensitivity inhibition at the level of mast cell degranulation and ceramide kinase activity. It may also be used to understand its potential antidiabetic activity and its neuroprotective activity via activation of the Nrf2/ARE signaling pathway.
Biochem/physiol Actions
Eriodictyolis absorbed in the body slowly and can be found in plasma and urine as homoeriodictyol, a conjugated form. It has many pharmacological properties such as antioxidant, anti-inflammatory, anti-cancer, anti-diabetic, anti-obesity, neuroprotective, cardioprotective, and hepatoprotective.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
For this product we use the non-stereospecific CAS number. It is expected that the natural enantiomer is predominant, however the substance is prone to racemization in solution. The product is therefore not specified stereospecifically and is only recommended to be used for non-stereospecific analysis.
Storage Class Code
11 - Combustible Solids
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Anowarul Islam et al.
Archives of pharmacal research, 43(6), 582-592 (2020-07-01)
Eriodictyol is a flavonoid in the flavanones subclass. It is abundantly present in a wide range of medicinal plants, citrus fruits, and vegetables that are considered to have potential health importance. Having the considerable medicinal properties, eriodictyol has been predicted
Minpei Kuroda et al.
Natural product communications, 7(4), 471-474 (2012-05-12)
MeOH extracts of 37 herbs were tested in screening experiments for rat intestinal alpha-glucosidase. The MeOH extract of the aerial parts of Scutellaria lateriflora L. (Lamiaceae) significantly inhibited sucrase and maltase activities, using sucrose and maltase as the substrates. Enzyme
Ángel Amesty et al.
Journal of natural products, 74(5), 1061-1065 (2011-04-21)
Three new benzodihydrofurans (1-3) and seven known aromatic compounds (4-10) were isolated from the roots of Cyperus teneriffae. Vibrational circular dichroism spectroscopy was used to define the absolute configuration of 1.
Zirong Deng et al.
Evidence-based complementary and alternative medicine : eCAM, 2020, 6681352-6681352 (2021-01-09)
Eriodictyol is a flavonoid that belongs to a subclass of flavanones and is widespread in citrus fruits, vegetables, and medicinally important plants. Eriodictyol has been anticipated to explain the method of its activity via multiple cellular signaling cascades. Eriodictyol is
Jakob P Ley et al.
Journal of agricultural and food chemistry, 53(15), 6061-6066 (2005-07-21)
Products made from Herba Santa (Eriodictyon californicum (H. & A.) Torr.) have been used as bitter remedies for some pharmaceutical applications for many years, but they are actually too aromatic to be useful for many food or pharmaceutical applications. In
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