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C1290

Supelco

Chlorpropamide

analytical standard, ≥97%

Synonym(s):

1-(p-Chlorobenzenesulfonyl)-3-propylurea

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About This Item

Empirical Formula (Hill Notation):
C10H13ClN2O3S
CAS Number:
94-20-2
Molecular Weight:
276.74
EC Number:
202-314-5
MDL number:
MFCD00079004
UNSPSC Code:
41116107
PubChem Substance ID:
329774748
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥97%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1

InChI

1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)

InChI key

RKWGIWYCVPQPMF-UHFFFAOYSA-N

Gene Information

human ... ABCC8(6833) , ALB(213) , EPHX2(2053) , KCNJ1(3758) , KCNJ11(3767)
mouse ... Ephx2(13850)

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General description

Chlorpropamide is a drug that belongs to the sulfonylurea family. It is an effective candidate in the treatment of diabetes insipidus.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H302,H361f

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
WXBD8089V
WXBD2909V
MKCK3785
MKCC2787
MKBX5489V

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Dong-Gyun Han et al.
Pharmaceutics, 13(2) (2021-02-03)
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Yury V Seryotkin et al.
Acta crystallographica. Section B, Structural science, 69(Pt 1), 77-85 (2013-02-01)
The crystal structure of the high-pressure polymorph (α') of an antidiabetic drug, chlorpropamide [4-chloro-N-(propylaminocarbonyl)benzenesulfonamide, C(10)H(13)ClN(2)O(3)S], which is formed at ~2.8 GPa from the α-polymorph (P2(1)2(1)2(1)) on hydrostatic compression in saturated ethanol solution, has been determined. As a result of the
Qing Zhu et al.
Molecular pharmaceutics, 7(4), 1291-1300 (2010-06-17)
As a result of an increase in the number of emerging therapies with dissolution limited bioavailability, formulation strategies such as solid dispersions that enhance the rate of solubilization are of interest. In this study, the microstructure of solid dispersions prepared
Jer-Yen Yang et al.
Cancer research, 70(11), 4709-4718 (2010-05-21)
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