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Ethyl methanesulfonate

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Synonym(s):

Ethyl mesylate, Methanesulfonic acid ethyl ester

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About This Item

Linear Formula:
CH3SO3CH2CH3
CAS Number:
Molecular Weight:
124.16
Beilstein:
773969
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
TraceCERT®

Quality Level

product line

TraceCERT®

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.418 (lit.)

bp

85-86 °C/10 mmHg (lit.)

density

1.206 g/mL at 20 °C

application(s)

environmental
pharmaceutical

format

neat

storage temp.

−20°C

SMILES string

CCOS(C)(=O)=O

InChI

1S/C3H8O3S/c1-3-6-7(2,4)5/h3H2,1-2H3

InChI key

PLUBXMRUUVWRLT-UHFFFAOYSA-N

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General description

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

212.0 °F

Flash Point(C)

100 °C


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Certificates of Analysis (COA)

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Mingguang Lei et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(1), 527-532 (2013-11-20)
DNA methylation is important for the silencing of transposons and other repetitive elements in many higher eukaryotes. However, plant and mammalian genomes have evolved to contain repetitive elements near or inside their genes. How these genes are kept from being
Benjamin Hartwig et al.
Plant physiology, 160(2), 591-600 (2012-07-28)
Mapping-by-sequencing (or SHOREmapping) has revitalized the powerful concept of forward genetic screens in plants. However, as in conventional genetic mapping approaches, mapping-by-sequencing requires phenotyping of mapping populations established from crosses between two diverged accessions. In addition to the segregation of
Tendekai Mahlanza et al.
Plant cell reports, 32(2), 249-262 (2012-10-24)
KEY MESSAGE : A combination of in vitro culture and mutagenesis using ethyl methanesulfonate (EMS) followed by culture filtrate-mediated selection produced variant sugarcane plants tolerant and resistant to Fusarium sacchari. Eldana saccharina is a destructive pest of the sugarcane crop
Catherine Charles et al.
Food chemistry, 135(4), 2974-2981 (2012-09-18)
The complexity of DNA repair mechanisms infers that xenobiotics, derived from food and medicinal plants, may interfere in the process, activating or inhibiting repair. Different flavonoids were investigated, at the highest non-toxic concentration, for their capacity to modulate DNA repair
G A Sega
Mutation research, 134(2-3), 113-142 (1984-09-01)
Ethyl methanesulfonate (EMS) is a monofunctional ethylating agent that has been found to be mutagenic in a wide variety of genetic test systems from viruses to mammals. It has also been shown to be carcinogenic in mammals. Alkylation of cellular

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