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Supelco

Oryzalin

PESTANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C12H18N4O6S
CAS Number:
19044-88-3
Molecular Weight:
346.36
Beilstein:
2177305
EC Number:
242-777-0
MDL number:
MFCD00078725
UNSPSC Code:
41116107
PubChem Substance ID:
329755324
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

SMILES string

CCCN(CCC)c1c(cc(cc1[N+]([O-])=O)S(N)(=O)=O)[N+]([O-])=O

InChI

1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)

InChI key

UNAHYJYOSSSJHH-UHFFFAOYSA-N

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General description

Oryzalin is a dinitroaniline herbicide, which can have the tendency to inhibit spindle formation and thereby lead to choromosome doubling in vitro in the diploid hybrid of Rosa rugosa. It can also serve as a potent antiparasitic therapeutic candidate, in the treatment of leishmaniasis disease.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Warning

Hazard Statements

H317,H351,H373,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Skin Sens. 1 - STOT RE 2

Target Organs

Blood,Kidney

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL8114
BCCG0802
BCCB2195
BCBZ8664
SZBE118XV

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Chromosome doubling in a Rosa rugosa Thunb. hybrid by exposure of in vitro nodes to oryzalin: the effects of node length, oryzalin concentration and exposure time
Allum.F.J, et al.
Plant Cell Reports, 26(11), 1977-1984 (2007)
Andrew Muroyama et al.
Current biology : CB, 30(22), 4467-4475 (2020-09-19)
Multicellular development depends on generating and precisely positioning distinct cell types within tissues. During leaf development, pores in the epidermis called stomata are spaced at least one cell apart for optimal gas exchange. This pattern is primarily driven by iterative
William Eisinger et al.
Molecular plant, 5(3), 601-610 (2012-03-10)
Radially arranged cortical microtubules are a prominent feature of guard cells. Guard cells expressing GFP-tubulin showed consistent changes in the appearance of microtubules when stomata opened or closed. Guard cells showed fewer microtubule structures as stomata closed, whether induced by
Molla M Endeshaw et al.
Bioorganic & medicinal chemistry letters, 20(17), 5179-5183 (2010-08-03)
The synthesis and evaluation of 20 dinitroanilines and related compounds against the obligate intracellular parasite Toxoplasma gondii is reported. Using in vitro cultures of parasites in human fibroblasts, we determined that most of these compounds selectively disrupted Toxoplasma microtubules, and
Sally Lyons-Abbott et al.
Eukaryotic cell, 9(12), 1825-1834 (2010-09-28)
Plant and protozoan microtubules are selectively sensitive to dinitroanilines, which do not disrupt vertebrate or fungal microtubules. Tetrahymena thermophila is an abundant source of dinitroaniline-sensitive tubulin, and we have modified the single T. thermophila α-tubulin gene to create strains that
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