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32593

Supelco

Cambendazole

VETRANAL®, analytical standard

Synonym(s):

Isopropyl 2-(4-thiazolyl)-5-benzimidazolecarbamate

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About This Item

Empirical Formula (Hill Notation):
C14H14N4O2S
CAS Number:
26097-80-3
Molecular Weight:
302.35
Beilstein:
563292
EC Number:
247-459-5
MDL number:
MFCD00864552
UNSPSC Code:
41116107
PubChem Substance ID:
329754047
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CC(C)OC(=O)Nc1ccc2[nH]c(nc2c1)-c3cscn3

InChI

1S/C14H14N4O2S/c1-8(2)20-14(19)16-9-3-4-10-11(5-9)18-13(17-10)12-6-21-7-15-12/h3-8H,1-2H3,(H,16,19)(H,17,18)

InChI key

QZWHWHNCPFEXLL-UHFFFAOYSA-N

General description

Cambendazole is classified under the family of benzimidazole anthelmintic compounds.

Application

Cambendazole may be used as an analytical reference standard for the determination of the analyte in:
  • Bovine muscle samples by ultra-high performance liquid chromatography (UHPLC) coupled to tandem mass spectrometry (MS/MS) operating in ESI mode.
  • Bovine milk samples by LC-ESI-MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Product No.
Description
Pricing

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H361fd

Hazard Classifications

Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK1453
BCCF0930
BCBZ9917
BCBW6201
BCBS4988V

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Determination of benzimidazoles and levamisole residues in milk by liquid chromatography-mass spectrometry: screening method development and validation.
Jedziniak P, et al.
Journal of Chromatography A, 1216(46), 8165-8172 (2009)
C Bauer et al.
Veterinary parasitology, 21(3), 189-203 (1986-08-01)
The prevalence of benzimidazole-resistant small strongyles was determined in a survey, conducted on 14 thoroughbred studs, which compared the faecal egg counts of groups of horses before and after treatment with the recommended doses of cambendazole (20 mg kg-1 b.w.)
H J Bürger et al.
The Veterinary record, 120(13), 293-296 (1987-03-28)
In order to confirm benzimidazole resistance as recommended at a workshop of the Commission of the European Communities the isolate 'E' of cyathostome strongyles originating from a stud where benzimidazole resistance had been demonstrated by egg hatch tests and by
Nader S Abutaleb et al.
Antimicrobial agents and chemotherapy, 64(6) (2020-04-08)
Clostridioides difficile, the leading cause of nosocomial infections, is an urgent health threat worldwide. The increased incidence and severity of disease, the high recurrence rates, and the dearth of effective anticlostridial drugs have created an urgent need for new therapeutic
D I Grove et al.
Transactions of the Royal Society of Tropical Medicine and Hygiene, 82(1), 146-149 (1988-01-01)
The effects of three benzimidazole anthelmintics in dogs infected with a human strain of Strongyloides stercoralis were investigated. Cambendazole, but not thiabendazole or mebendazole, abrogated the subsequent development of a patent infection when administered at the same time as infection
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