Skip to Content
Merck
All Photos(1)

Documents

03338

Supelco

α-Arbutin

analytical standard

Synonym(s):

4-Hydroxyphenyl α-D-glucopyranoside, Hydroquinone O-α-D-glucopyranoside

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C12H16O7
CAS Number:
Molecular Weight:
272.25
Beilstein:
89675
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥99% (HPLC and GC)

shelf life

limited shelf life, expiry date on the label

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC2=CC=C(O)C=C2

InChI

1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12+/m1/s1

InChI key

BJRNKVDFDLYUGJ-ZIQFBCGOSA-N

General description

α-Arbutin is a glycosylated hydroquinone and an anomer of naturally occurring arbutin. It is a potent inhibitor of tyrosinase, a vital enzyme involved in epidermal melanin biosynthesis. α-Arbutin finds extensive application as a powerful skin-lightening agent in cosmetic industries.

Application

α-Arbutin may be used as an analytical reference standard for the determination of the analyte in cosmetics by high-performance liquid chromatography with UV detection (HPLC-UV) method.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Syntheses of arbutin-$\alpha$-glycosides and a comparison of their inhibitory effects with those of $\alpha$-arbutin and arbutin on human tyrosinase
Sugimoto K, et al.
Chemical & Pharmaceutical Bulletin, 51(7), 798-801 (2003)
Isolation of $\alpha$-arbutin from Xanthomonas CGMCC 1243 fermentation broth by macroporous resin adsorption chromatography
Liu C, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 925, 104-109 (2013)
Syntheses of $\alpha$-arbutin-$\alpha$-glycosides and their inhibitory effects on human tyrosinase
Sugimoto K, et al.
Journal of Bioscience and Bioengineering, 99(3), 272-276 (2005)
Quantitative determination of $\alpha$-arbutin, $\beta$-arbutin, kojic acid, nicotinamide, hydroquinone, resorcinol, 4-methoxyphenol, 4-ethoxyphenol, and ascorbic acid from skin whitening products by HPLC-UV
Wang YH, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 98(1), 5-12 (2015)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service