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05-143

Sigma-Aldrich

Anti-PLA2 Antibody, secretory

Upstate®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified antibody

clone

monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgG1κ

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Specificity

human type II secretory PLA2 in sperm, disc and synovial fluid

Immunogen

Purified human PLA2; recognizes type II (secretory) PLA2.

Application

Research Category
Signaling
Research Sub Category
Lipid Signaling
This Anti-PLA2 Antibody, secretory is validated for use in ELISA, IH, WB for the detection of PLA2.

Quality

routinely evaluated on PLA2 under non-reducing conditions

Target description

14/18 kDa

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl with 0.05% sodium azide
DEAE cellulose chromatography
Format: Purified

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Detection of natural peptide antibiotics in human nasolacrimal ducts.
F P Paulsen, T Pufe, U Schaudig, J Held-Feindt, J Lehmann, J M Schroder, B N Tillmann
Investigative Ophthalmology & Visual Science null
X D Qu et al.
Infection and immunity, 66(6), 2791-2797 (1998-05-29)
We examined human tears for molecules that killed gram-positive bacteria. The principal mediator of bactericidal activity against staphylococci proved to be a calcium-dependent enzyme, secretory phospholipase A2. Whereas the concentration of secretory phospholipase A2 in the normal tear film exceeded
G Dorsam et al.
Clinical chemistry, 41(6 Pt 1), 862-866 (1995-06-01)
Previously we reported that uremic plasma contained eight times more phospholipase A2 (PLA2) activity than control plasma (Costello et al., Clin Chem 1990;36:198-200). That study, however, did not distinguish between various PLA2s that could contribute to the observed increase. Therefore
Angiotensin II type 2 receptor stimulation of neuronal delayed-rectifier potassium current involves phospholipase A2 and arachidonic acid
Zhu, M., et al
The Journal of Neuroscience, 18, 679-686 (1998)
Yan Fu et al.
Journal of neuroscience research, 85(13), 2870-2881 (2007-06-07)
Coherent anti-Stokes Raman scattering (CARS) microscopy, which allows vibrational imaging of myelin sheath in its natural state, was applied to characterize lysophosphatidylcholine (lyso-PtdCho)-induced myelin degradation in tissues and in vivo. After the injection of lyso-PtdCho into ex vivo spinal tissues

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