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810132C

Avanti

18:1-06:0 NBD PC

Avanti Research™ - A Croda Brand 810132C

Synonym(s):

1-oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C38H64N5O11P
CAS Number:
106974-05-4
Molecular Weight:
797.92
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810132C-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810132C

concentration

1 mg/mL (810132C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

Phosphocholine is considered as a precursor molecule. It is formed during the breakdown of phosphatidylcholine (PC) metabolism. 18:1-06:0 NBD PC is a fluorescent lipid analog/probe.

Application

18:1-06:0 NBD PC is suitable for use:
  • as a component in preparing lipid solution for bilayer formation
  • to use as a single donor in fluorescence resonance energy transfer (FRET) based assay
  • to prepare phospholipid-coated beads

Biochem/physiol Actions

NBD‐PC can be used to probe the existence of (Rho‐labeled) protease‐activated receptor (PAR) pepducins in the outer and inner leaflets.

Packaging

5 mL Amber Glass Screw Cap Vial (810132C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Large scale biomimetic membrane arrays
Hansen JS, et al.
Analytical and Bioanalytical Chemistry, 395(3), 719-727 (2009)
Anticoagulant and antithrombotic properties of intracellular protease-activated receptor antagonists
Wielders SJH, et al.
Journal of Thrombosis and Haemostasis, 5(3), 571-576 (2007)
Coordinated balance of Rac1 and RhoA plays key roles in determining phagocytic appetite
Kim SY, et al.
PLoS ONE, 12(4), e0174603-e0174603 (2017)
Yuta Ryoden et al.
Journal of immunology (Baltimore, Md. : 1950), 204(3), 559-568 (2019-12-22)
In response to extracellular ATP, the purinergic receptor P2X7 mediates various biological processes, including phosphatidylserine (PtdSer) exposure, phospholipid scrambling, dye uptake, ion transport, and IL-1β production. A genome-wide CRISPR screen for molecules responsible for ATP-induced PtdSer exposure identified a transmembrane
Chung Park et al.
eLife, 8 (2019-12-04)
During human immunodeficiency virus-1 (HIV-1) infection lymphoid organ follicular dendritic cells (FDCs) serve as a reservoir for infectious virus and an obstacle to curative therapies. Here, we identify a subset of lymphoid organ sinus lining macrophage (SMs) that provide a
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