715492

4-(Dimethylcarbamoyl)phenylboronic acid

≥94%

• Synonym(s): (4-(Dimethylaminocarbonyl)phenyl)boronic acid, 4-(N,N-Dimethylaminocarbonyl)phenylboronic acid, 4-(Dimethylcarbamoyl)benzeneboronic acid, 4-Dimethylcarbamoylphenylboronic acid, [4-(N,N-Dimethylaminocarbonyl)phenyl]boronic acid, [4-(N,N-Dimethylcarbamoyl)phenyl]boronic acid
• Empirical Formula (Hill Notation): C₉H₁₂BNO₃
• CAS Number: 405520-68-5
• Molecular Weight: 193.01
• MDL number: MFCD02258943
• UNSPSC Code: 12352103
• PubChem Substance ID: 329762975
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥94%
• form: solid
• mp: 141-145 °C
• storage temp.: 2-8°C
• SMILES string: CN(C)C(=O)c1ccc(cc1)B(O)O
• InChI: 1S/C9H12BNO3/c1-11(2)9(12)7-3-5-8(6-4-7)10(13)14/h3-6,13-14H,1-2H3
• InChI key: QJYYVSIRDJVQJW-UHFFFAOYSA-N

Description

General description

May contain varying amounts of anhydride

Application

Reactant for preparation of:

• Selective glucocorticoid receptor agonists
• (thienopyridine)carboxamides as checkpoint 1 kinase (CHK1) inhibitors
• [(pyrrolo[2,3-b]pyridinyl)methylene]hydroxybenzofuranones as ATP-competitive inhibitors of the mammalian target of rapamycin
• Pyrrolopyridines as inhibitors of insulin-like growth factor-1 receptor tyrosine kinase

Reactant for:

• Copper-mediated N-arylation of quinazolinediones

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable