Skip to Content
Merck
All Photos(3)

Documents

318183

Sigma-Aldrich

Methyl sulfate sodium salt

Synonym(s):

Monomethyl ester sulfuric acid sodium salt, Sodium methyl sulfate

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Linear Formula:
CH3OSO3Na
CAS Number:
512-42-5
Molecular Weight:
134.09
EC Number:
208-142-7
MDL number:
MFCD00013457
UNSPSC Code:
12352100
PubChem Substance ID:
24859116
NACRES:
NA.22

form

powder

impurities

<3% methanol
<5% water

mp

210 °C (lit.)

SMILES string

[Na+].COS([O-])(=O)=O

InChI

1S/CH4O4S.Na/c1-5-6(2,3)4;/h1H3,(H,2,3,4);/q;+1/p-1

InChI key

DZXBHDRHRFLQCJ-UHFFFAOYSA-M

Application

Methyl sulfate sodium salt can be used to synthesize:
  • Methylsulfate anion based 1,3,4-trialkyl-1,2,3-triazolium ionic liquids for use in Morita–Baylis–Hillman reaction.
  • Anisole by reacting with phenol.
  • Hydroxyanilino quinolines for use as RET kinase inhibitors.

Reactant or reagent involved in:
  • Studying lamellar structure formation in hybrid nanomaterials created by miniemulsion
  • EPR studies of radical ions radiolytically generated from ionic liquids, used as a reference
  • Micellular studies specifically the rate-retarding effects on hydrolysis of substituted 1-benzoyl-1,2,4-triazoles and self-assembly / microstructure of mixed micelles

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 + H332,H315,H335

Hazard Classifications

Acute Tox. 4 Oral - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

Octadecyl sulfate sodium salt technical grade, 93%

Sigma-Aldrich

293946

Octadecyl sulfate sodium salt

Ethyl-d5 sulfate sodium salt 1.0&#160;mg/mL in methanol (as ethyl sulfate), ampule of 1&#160;mL, certified reference material, Cerilliant&#174;

Supelco

E-066

Ethyl-d5 sulfate sodium salt

The discovery of substituted 4-(3-hydroxyanilino)-quinolines as potent RET kinase inhibitors
Robinett R G, et al.
Bioorganic & Medicinal Chemistry Letters, 17(21), 5886-5893 (2007)
Synthesis of anisole from phenol and sodium methyl sulfate, a byproduct from synthesis of medicine intermediates
Guoping W, et al.
Petrochemical Technology, 45(11), 1337-1337 (2016)
Synthesis of new triazolium-based ionic liquids and their use in the Morita-Baylis-Hillman reaction
F Alioune, et al.
Tetrahedron Letters, 56(36), 5128-5131 (2015)
Richard Wolfenden et al.
Proceedings of the National Academy of Sciences of the United States of America, 104(1), 83-86 (2006-12-22)
Alkyl sulfate monoesters are involved in cell signaling and structure. Alkyl sulfates are also present in many commercial detergents. Here, we show that monomethyl sulfate acts as an efficient alkylating agent in water, reacting spontaneously with oxygen nucleophiles >100-fold more
Sayantan Bose et al.
Biotechnology and bioengineering, 109(2), 434-443 (2011-10-19)
We discuss the hydrolysis of cellulose using a pure cellulase: endo-1,4-β-D-glucanase (EG) from the fungus, Aspergillus niger, in buffer, the pure ionic liquid (IL), tris-(2-hydroxyethyl)-methylammonium methylsulfate (HEMA), and various mixtures of the two at different temperatures. Steady-state fluorescence and absorbance
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service