196479
2-Phenyl-4-quinolinecarboxylic acid
99%
Synonym(s):
2-Phenylcinchoninic acid, Cinchophen
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About This Item
Empirical Formula (Hill Notation):
C16H11NO2
CAS Number:
Molecular Weight:
249.26
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
99%
form
powder
mp
214-215 °C (lit.)
solubility
alcohol: soluble 1g in 120ml(lit.)
chloroform: soluble 1g in 400ml(lit.)
diethyl ether: soluble 1g in 100ml(lit.)
water: insoluble(lit.)
SMILES string
OC(=O)c1cc(nc2ccccc12)-c3ccccc3
InChI
1S/C16H11NO2/c18-16(19)13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H,(H,18,19)
InChI key
YTRMTPPVNRALON-UHFFFAOYSA-N
Related Categories
General description
2-Phenyl-4-quinolinecarboxylic acid on reaction with 5-aryl-2,3-dihydro-2,3-furandiones yields β-aroylpyruvoyl hydrazide of 2-phenyl-4-quinolinecarboxylic acid.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Amides and hydrazides of aroylpyrivic acids. Part 6 Synthesis and study of antiinflammatory and analgesic activity of ?-aroylpyruvoyl hydrazides of 2-methyl (phenyl)-4-quinolinecarboxylic acids.
Milyutin AV, et al.
Pharmaceutical Chemistry Journal, 32(8), 422-424 (1998)
[DISTRIBUTION AND CONTENT OF RIBONUCLEOPROTEINS IN THE SMALL INTESTINE MUCOUS MEMBRANE IN CHRONIC EXPERIMENTAL STOMACH ULCER IN DOGS].
S A DALIMOV et al.
Meditsinskii zhurnal Uzbekistana, 39, 50-53 (1963-08-01)
[Gout].
Y OSHIMA
Naika. Internal medicine, 10, 1101-1102 (1962-12-01)
[Contributions to evaluation of the substances inhibiting inflammation].
F VARGA et al.
Acta physiologica Academiae Scientiarum Hungaricae, 23, 69-78 (1963-01-01)
H Jingu et al.
Neuroreport, 7(15-17), 2649-2653 (1996-11-04)
This study aimed at obtaining evidence that cinchophen, an ulcerogenic drug, stimulates the corticotropin-releasing hormone (CRH)-secreting cells in the paraventricular nucleus of the hypothalamus (PVH) to induce c-Fos expression. Without colchicine pretreatment, cinchophen was injected i.p. 60 min before the
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