Trifluoroacetamide is a good quencher of tryptophan fluorescence[1].
Application
Trifluoroacetamide was used as probe for determination of membrane potential and extra/intracellular volume of erythrocytes by fluorine-19 NMR studies[2].
Biochimica et biophysica acta, 801(1), 16-25 (1984-09-07)
Trifluoroacetamide was found to be a good quencher of tryptophan fluorescence, and the quenching was shown to proceed via both a dynamic and a static process. The respective quenching constants were determined by the measurement of the decrease of the
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