SAB4502013

Anti-ENOS antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Constitutive NOS, EC-NOS, ECNOS, Endothelial NOS, cNOS
• MDL number: MFCD00675266
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 133 kDa
• species reactivity: human, rat, mouse
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:40000; western blot: 1:500-1:1000
• NCBI accession no.: P29474
• UniProt accession no.: P29474
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... NOS3(4846)

Description

General description

Anti-ENOS Antibody detects endogenous levels of total ENOS protein.

The ENOS (endothelial nitric oxide synthase) gene is mapped to human chromosome 7q36.1. ENOS is expressed predominantly in the endothelial cells.

Immunogen

The antiserum was produced against synthesized peptide derived from human eNOS.

Immunogen Range: 581-630

Application

Anti-ENOS antibody produced in rabbit has been used in SDS-PAGE and western blotting.

Biochem/physiol Actions

ENOS (endothelial nitric oxide synthase) is responsible for the production of nitric oxide. eNOS is known to stimulate vasodilation and regulate inflammation and myocyte function. Impairment of endothelium-dependent vasodilatation that is observed in acute hyperglycaemia condition is due to suppression of ENOS. The gene might be involved in lipolysis. Variation in ENOS might lead to Henoch-Schönlein purpura. ENOS polymorphism affects the NO concentration in plasma.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable