Skip to Content
Merck
All Photos(5)

Key Documents

View All Documentation

N3501

Sigma-Aldrich

β-Nicotinamide mononucleotide

≥95% (HPLC)

Synonym(s):

β-NMN, β-Nicotinamide ribose monophosphate, NMN, Nicotinamide ribotide, Nicotinamide-1-ium-1-β-D-ribofuranoside 5′-phosphate

Sign Into View Organizational & Contract Pricing
All Photos(5)

About This Item

Empirical Formula (Hill Notation):
C11H15N2O8P
CAS Number:
1094-61-7
Molecular Weight:
334.22
Beilstein:
3570187
EC Number:
214-136-5
MDL number:
MFCD00038748
UNSPSC Code:
41106305
PubChem Substance ID:
24897645
NACRES:
NA.51

Assay

≥95% (HPLC)
≥95% (spectrophotometric assay)

form

powder

storage temp.

−20°C

SMILES string

C[C@H]1[C@@H](C)[C@@H](O[C@@H]1COP(O)([O-])=O)[n+]2cccc(c2)C(N)=O

InChI

1S/C13H19N2O6P/c1-8-9(2)13(21-11(8)7-20-22(17,18)19)15-5-3-4-10(6-15)12(14)16/h3-6,8-9,11,13H,7H2,1-2H3,(H3-,14,16,17,18,19)/t8-,9+,11+,13+/m0/s1

InChI key

YYNOOWWEYJELSF-SEMCEJNYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

β-Nicotinamide mononucleotide (β-NMN) is an intermediate in the nicotinamide phosphoribosyltransferase (NAMPT)-catalyzed biosynthesis of nicotinamide adenine dinucleotide (NAD+). NAMPT mediates the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to produce β-NMN. β-NMN adenyltransferase subsequently converts β-NMN to NAD+.

Application

β-Nicotinamide mononucleotide (NMN) is used to study binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.

Other Notes

Note: This is the common form of NMN. Do not confuse it with α-NMN.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Jun Yoshino et al.
Cell metabolism, 14(4), 528-536 (2011-10-11)
Type 2 diabetes (T2D) has become epidemic in our modern lifestyle, likely due to calorie-rich diets overwhelming our adaptive metabolic pathways. One such pathway is mediated by nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme in mammalian NAD(+) biosynthesis, and the NAD(+)-dependent
Shin-Ichiro Imai
Pharmacological research, 62(1), 42-47 (2010-01-21)
Aging science has recently drawn much attention, and discussions on the possibility of anti-aging medicine have multiplied. One potential target for the development of anti-aging drugs is the SIR2 (silent information regulator 2) family of NAD-dependent deacetylases/ADP-ribosyltransferases, called "sirtuins." Sirtuins
Gerwyn Morris et al.
Progress in neuro-psychopharmacology & biological psychiatry, 95, 109708-109708 (2019-07-28)
Major antioxidant responses to increased levels of inflammatory, oxidative and nitrosative stress (ONS) are detailed. In response to increasing levels of nitric oxide, S-nitrosylation of cysteine thiol groups leads to post-transcriptional modification of many cellular proteins and thereby regulates their
João Meireles Ribeiro et al.
Scientific reports, 8(1), 1036-1036 (2018-01-20)
Cyclic ADP-ribose (cADPR) is a messenger for Ca
C T Lauhon et al.
Journal of the American Chemical Society, 117(4), 1246-1257 (1995-02-01)
RNA molecules that specifically bind riboflavin (Rb) and beta-nicotinamide mononucleotide (NMN) have been isolated by in vitro selection. A simple structural motif containing intramolecular G-quartets was found to bind tightly to oxidized riboflavin (Kd = 1-5 micromolar). DNA versions of
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service