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M5760

Sigma-Aldrich

4-(4-Methoxybenzylamino)-7-nitrobenzofurazan

>97.5% purity (HPLC), powder

Synonym(s):

4-(4-Methoxybenzylamino)-7-nitro-2,1,3-benzoxadiazole, MBD

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About This Item

Empirical Formula (Hill Notation):
C14H12N4O4
CAS Number:
33984-50-8
Molecular Weight:
300.27
Beilstein:
1151390
EC Number:
251-775-9
MDL number:
MFCD00042778
UNSPSC Code:
12171500
PubChem Substance ID:
24897041
NACRES:
NA.47

product name

4-(4-Methoxybenzylamino)-7-nitrobenzofurazan,

Assay

>97.5% (HPLC)

form

powder

color

orange to red

solubility

DMSO:methanol (1:1): 50 mg/mL, clear, orange

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

COc1ccc(CNc2ccc([N+]([O-])=O)c3nonc23)cc1

InChI

1S/C14H12N4O4/c1-21-10-4-2-9(3-5-10)8-15-11-6-7-12(18(19)20)14-13(11)16-22-17-14/h2-7,15H,8H2,1H3

InChI key

IENONFJSMWUIQQ-UHFFFAOYSA-N

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Related Categories

Application

Fluorescent probe for hydrophobic (non-polar) regions in proteins and nucleoproteins.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ke Liu et al.
The FEBS journal, 286(16), 3240-3254 (2019-04-14)
The MBD3, a methyl-CpG-binding domain (MBD)-containing protein, is a core subunit of the Mi-2/NuRD complex. Recent reports show that MBD3 recognizes both methylated CG (mCG)- and hydroxymethylated CG (hmCG)-containing DNA, with a preference for hmCG. However, whether the MBD3-MBD indeed
Sevda Tanrıkulu-Küçük et al.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 44(7), 774-782 (2019-01-04)
This study investigated the effects of curcumin and capsaicin on testicular and hepatic oxidant-antioxidant status in rats fed a high-fat diet (HFD). Male Sprague-Dawley rats were divided into 5 groups (8 rats per group). The control group was fed a
Yu Nakamichi et al.
Scientific reports, 9(1), 6466-6466 (2019-04-25)
Despite extensive research on primate cognitive function, understanding how anatomical connectivity at a neural circuit level relates to information transformation across different cortical areas remains primitive. New technology is needed to visualize inter-areal anatomical connectivity in living monkeys and to
Benjamin C Buchmuller et al.
Scientific reports, 10(1), 4053-4053 (2020-03-07)
5-Methylcytosine (mC) exists in CpG dinucleotides of mammalian DNA and plays key roles in chromatin regulation during development and disease. As a main regulatory pathway, fully methylated CpG are recognized by methyl-CpG-binding domain (MBD) proteins that act in concert with
Alessia Armezzani et al.
Development (Cambridge, England), 145(11) (2018-05-10)
The shoot apical meristem of higher plants continuously generates new tissues and organs through complex changes in growth rates and directions of its individual cells. Cell growth, which is driven by turgor pressure, largely depends on the cell walls, which
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