H6515

L-Homoserine

• Synonym(s): (S)-2-Amino-4-hydroxybutyric acid, Hse
• Linear Formula: HOCH₂CH₂CH(NH₂)CO₂H
• CAS Number: 672-15-1
• Molecular Weight: 119.12
• Beilstein: 1721681
• EC Number: 211-590-6
• MDL number: MFCD00063090
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24895748
• NACRES: NA.26

Properties

• Assay: ≥98% (TLC)
• form: powder
• color: white to off-white
• mp: 203 °C (dec.) (lit.)
• application(s): cell analysis; detection
• SMILES string: N[C@@H](CCO)C(O)=O
• InChI: 1S/C4H9NO3/c5-3(1-2-6)4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m0/s1
• InChI key: UKAUYVFTDYCKQA-VKHMYHEASA-N

Description

General description

L-Homoserine is a variant of serine with an additional carbon on its side chain.

Application

L-Homoserine has been used as an internal standard for neurotransmitter analysis and amino acids quantification.

Biochem/physiol Actions

L-Homoserine is synthesized by deoxidation process, catalysed by homoserine dehydrogenase. This is one of the steps in the synthesis of L-threonine. The carbon flux in in bacteria such as E. coli is maintained by this reaction.

L-Homoserine is used in the biosynthesis of methionine, threonine and isoleucine.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves