G1149

L-Glutamic acid potassium salt monohydrate

BioReagent, suitable for insect cell culture, ≥99% (HPLC)

• Synonym(s): (S)-2-Aminopentanedioic acid, L-α-Aminoglutaric acid potassium salt, L-2-Aminopentanedioic acid potassium salt, Glu, Potassium L-glutamate
• Empirical Formula (Hill Notation): C₅H₈KNO₄ · H₂O
• CAS Number: 6382-01-0
• Molecular Weight: 203.23
• Beilstein: 3637377
• MDL number: MFCD00150343
• UNSPSC Code: 12352209
• PubChem Substance ID: 24895045
• NACRES: NA.75

Properties

• product line: BioReagent
• Assay: ≥99% (HPLC)
• form: powder
• technique(s): cell culture | insect: suitable
• color: white
• SMILES string: O.[K+].N[C@@H](CCC([O-])=O)C(O)=O
• InChI: 1S/C5H9NO4.K.H2O/c6-3(5(9)10)1-2-4(7)8;;/h3H,1-2,6H2,(H,7,8)(H,9,10);;1H2/q;+1;/p-1/t3-;;/m0../s1
• InChI key: XIBUKSQTWSKJMQ-QTNFYWBSSA-M

Description

General description

L-Glutamic acid, an amino acid is mainly found in various food products in its free form. It is ubiquitously present in the brain of mammals.

Application

L-Glutamic acid potassium salt monohydrate has been used as a component in KG buffer for cardiomyocyte isolation and culture.

Biochem/physiol Actions

L-Glutamic acid plays a major role in several metabolic pathways. It acts as excitatory neurotransmitter in the cerebral cortex. An plays a key role in learning, memory and brain aging processes. It is involved in neuronal differentiation, migration and survival in the developing brain. High levels of glutamic acid is observed in Alzheimer′s, Parkinson′s diseases and epilepsy.

Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H319
• Precautionary Statements: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves