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Key Documents

C8385

Sigma-Aldrich

Potassium citrate tribasic monohydrate

≥98% (GC/titration)

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About This Item

Empirical Formula (Hill Notation):
C6H5K3O7 · H2O
CAS Number:
Molecular Weight:
324.41
EC Number:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

Quality Level

Assay

≥98% (GC/titration)

form

powder

loss

3.0-6.0% loss on drying

pH

8.0-9.5

solubility

H2O: 100 mg/mL, clear, colorless

SMILES string

O.[K+].[K+].[K+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

InChI

1S/C6H8O7.3K.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;1H2/q;3*+1;/p-3

InChI key

PJAHUDTUZRZBKM-UHFFFAOYSA-K

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Application

Potassium citrate tribasic monohydrate has been used in interconnected porous carbon nanosheets (IPCNs) synthesis. It has also been used to study the use of clinical-grade Garcinia cambogia in Drosophila kidney stone models.

Biochem/physiol Actions

Potassium citrate can be used to prepare citrate water that supports the survival of streptozotocin (STZ)-diabetic mice. It might reduce the successive stone formation in calcium nephrolithiasis. Potassium citrate serves as an activator for producing activated carbons.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Clinical-grade Garcinia cambogia extract dissolves calcium oxalate crystals in Drosophila kidney stone models.
Fan, et al.
European Review for Medical and Pharmacological Sciences, 24, 6434-6445 (2021)
The synergistic effect of oxygen-containing functional groups on CO 2 adsorption by the glucose-potassium citrate-derived activated carbon
Liu B, et al.
Royal Society of Chemistry Advances, 8(68), 38965-38973 (2018)
Protective Effect of Topiramate on Hyperglycemia-Induced Cerebral Oxidative Stress, Pericyte Loss and Learning Behavior in Diabetic Mice
Price TO, et al.
Biochemical and biophysical research communications, 1, 6-12 (2015)
Mussel-inspired surface functionalization of porous carbon nanosheets using polydopamine and Fe 3+/tannic acid layers for high-performance electrochemical capacitors
Lee YA, et al.
Journal of Material Chemistry A, 5(48), 25368-25377 (2017)
Nancy S Krieger et al.
Journal of the American Society of Nephrology : JASN, 26(12), 3001-3008 (2015-04-10)
Potassium citrate is prescribed to decrease stone recurrence in patients with calcium nephrolithiasis. Citrate binds intestinal and urine calcium and increases urine pH. Citrate, metabolized to bicarbonate, should decrease calcium excretion by reducing bone resorption and increasing renal calcium reabsorption.

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