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C3279

Sigma-Aldrich

Copper(II) chloride dihydrate

powder, BioReagent, suitable for cell culture

Synonym(s):

Cupric chloride dihydrate

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About This Item

Linear Formula:
CuCl2 · 2 H2O
CAS Number:
10125-13-0
Molecular Weight:
170.48
EC Number:
231-210-2
MDL number:
MFCD00149674
UNSPSC Code:
12352205
PubChem Substance ID:
24892598
NACRES:
NA.75

biological source

synthetic (inorganic)

Quality Level

200

product line

BioReagent

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

water: 100 mg/mL, clear, blue

SMILES string

O.Cl[Cu]Cl

InChI

1S/2ClH.Cu.2H2O/h2*1H;;2*1H2/q;;+2;;/p-2

InChI key

MPTQRFCYZCXJFQ-UHFFFAOYSA-L

Application

Copper(II) chloride dihydrate has been used as a positive control in dispersion of zebrafish embryo. It has also been used for the preparation of trace metals mixture.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Soluble and Solid Iron Reduction Assays with Desulfitobacterium hafniense
Comensoli L, et al.
Bio-protocol, 8(ARTICLE), 340-340 (2018)
Man Long Kwok et al.
Metallomics : integrated biometal science, 12(5), 732-751 (2020-03-24)
All cells require Cu as a cofactor, but Cu2+ induces toxicity and oxidative damage. A strict system is thus needed to maintain Cu homeostasis. Using the ZFL zebrafish liver cell line as a model, we studied the cellular responses after
Copper-containing mesoporous bioactive glass promotes angiogenesis in an in vivo zebrafish model
Romero-Sanchez LB, et al.
Acta Biomaterialia, 68, 272-285 (2018)
Man Long Kwok et al.
Toxicology reports, 7, 822-835 (2020-07-17)
Copper (Cu) and cadmium (Cd) are widely used in industrial activities, resulting in Cu and Cd contamination in aquatic systems worldwide. Although Cu plays an essential role in many biological functions, an excessive amount of the metal causes cytotoxicity. In
Florida Voli et al.
Cancer research, 80(19), 4129-4144 (2020-08-21)
Therapeutic checkpoint antibodies blocking programmed death receptor 1/programmed death ligand 1 (PD-L1) signaling have radically improved clinical outcomes in cancer. However, the regulation of PD-L1 expression on tumor cells is still poorly understood. Here we show that intratumoral copper levels
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Articles

Copper in Cell Culture

Importance and uses of copper in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO), cell cultures

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