B6768

Boric acid

BioReagent, for molecular biology, suitable for cell culture, suitable for plant cell culture, ≥99.5%

• Linear Formula: H₃BO₃
• CAS Number: 10043-35-3
• Molecular Weight: 61.83
• EC Number: 233-139-2
• MDL number: MFCD00011337
• UNSPSC Code: 12161700
• eCl@ss: 38120104
• PubChem Substance ID: 24891821
• NACRES: NA.25

Properties

• grade: for molecular biology
• Quality Level: 200
• vapor pressure: 2.6 mmHg ( 20 °C)
• product line: BioReagent
• Assay: ≥99.5%
• form: powder
• technique(s): cell culture | mammalian: suitable; cell culture | plant: suitable
• pH: 5.1 (25 °C, 1.8 g/L)
• mp: 160 °C (dec.) (lit.)
• solubility: water: 40 mg/mL, clear, colorless
• density: 1.49 g/cm³ at 23 °C
• cation traces: Fe: ≤5 ppm; Mg: ≤5 ppm; heavy metals (as Pb): ≤10 ppm
• UV absorption: λ: 260 nm A_max: 0.05; λ: 280 nm A_max: 0.05
• foreign activity: DNase, RNase, and protease, none detected
• storage temp.: room temp
• SMILES string: OB(O)O
• InChI: 1S/BH3O3/c2-1(3)4/h2-4H
• InChI key: KGBXLFKZBHKPEV-UHFFFAOYSA-N

Description

General description

Boric acid is a weak monobasic Lewis acid (electron pair acceptor), which reacts reversibly with alcohols. It is used in dermal and women′s hygiene products due to its mild antibacterial and antifungal effects. Boric acid is used as a buffer in ophthalmic products. It acts as an effective solid lubrication agent because of its molecular structure. Boric acid finds its applications in glass making, fire retardant. Boric acid is used in biochemistry in buffer solutions. It also forms complex equilibria in solution, with the tetraborate ion (B4O7 2- ) being the predominant species. Borate buffers are involved in discontinuous electrophoresis and capillary electrophoresis systems for the separation of proteins and nucleic acids.

Application

Boric acid has been used:

• to prepare boric buffer for the quantification of primary amine groups at the surface of nanocapsules
• to study its effects on epigenetic change
• for the estimation of protein in wheatgrass using Kjeldahl method

Used to promote amidations of carboxylic acids and amines in catalytic amounts. This technology avoids the requirement of preactivation of the carboxylic acid or use of coupling reagents.
Intensified Azeotropic Distillation: A Strategy for Optimizing Direct Amidation

Features and Benefits

• Environment-friendly
• Non-toxic 

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H360FD
• Precautionary Statements: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves