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B4153

Sigma-Aldrich

Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride

~95%

Synonym(s):

Boc-Gln-Ala-Arg-AMC hydrochloride, Boc-Gln-Ala-Arg-Mca hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C29H42N8O8 · HCl
CAS Number:
113866-20-9
Molecular Weight:
667.15
MDL number:
MFCD00080216
UNSPSC Code:
12352204
PubChem Substance ID:
24891756
NACRES:
NA.32

Assay

~95%

form

powder

solubility

methanol: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

CC(NC(=O)C(CCC(N)=O)NC(=O)OC(C)(C)C)C(=O)NC(CCCNC(N)=N)C(=O)Nc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C29H42N8O8/c1-15-13-23(39)44-21-14-17(8-9-18(15)21)35-26(42)19(7-6-12-33-27(31)32)36-24(40)16(2)34-25(41)20(10-11-22(30)38)37-28(43)45-29(3,4)5/h8-9,13-14,16,19-20H,6-7,10-12H2,1-5H3,(H2,30,38)(H,34,41)(H,35,42)(H,36,40)(H,37,43)(H4,31,32,33)

InChI key

LQSLBVXESNRILG-UHFFFAOYSA-N

General description

Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride is a fluorogenic and cell-permeable trypsin substrate.

Application

Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride has been used as a fluorogenic substrate to measure the enzymatic activity of trypsin.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Substrates

Substrate for trypsin

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rotllant G, et al.
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