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A9125

Sigma-Aldrich

Nα-Acetyl-L-glutamine

≥98% (TLC)

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About This Item

Empirical Formula (Hill Notation):
C7H12N2O4
CAS Number:
2490-97-3
Molecular Weight:
188.18
Beilstein:
1727471
EC Number:
219-647-7
MDL number:
MFCD00038159
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24891229
NACRES:
NA.26

product name

Nα-Acetyl-L-glutamine,

Assay

≥98% (TLC)

form

powder

color

white

storage temp.

2-8°C

SMILES string

CC(=O)N[C@@H](CCC(N)=O)C(O)=O

InChI

1S/C7H12N2O4/c1-4(10)9-5(7(12)13)2-3-6(8)11/h5H,2-3H2,1H3,(H2,8,11)(H,9,10)(H,12,13)/t5-/m0/s1

InChI key

KSMRODHGGIIXDV-YFKPBYRVSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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I Magnusson et al.
Metabolism: clinical and experimental, 38(8 Suppl 1), 82-88 (1989-08-01)
L-glutamine is too unstable for inclusion in solutions for parenteral nutrition, but its acetylated analogue, N-acetyl-L-glutamine is not. The purpose of this three-part study was to investigate the utilization of intravenously (IV) administered acetylglutamine in humans. In study 1, nine
C Coudray-Lucas et al.
Clinical nutrition (Edinburgh, Scotland), 18(1), 29-33 (1999-08-25)
Glutamine is considered an essential nutrient for cellular growth. To test the suitability of alpha-ketoisocaproyl-Gln (Kic-Gln) as a new glutamine (Gln) precursor to sustain human fibroblast growth. [3H] thymidine uptake into cellular DNA of human fibroblasts. Extracellular and intracellular amino
F Drago et al.
Clinical neuropharmacology, 13(4), 290-296 (1990-08-01)
The pyrimidine nucleosides uridine (URI) and cytidine (CYT), alone or associated with n-acetyl-glutamine (NAG), were injected acutely or subchronically to aged (26 months old) male rats of the Sprague-Dawley strain. Learning and memory abilities of the animals were studied with
José M López-Pedrosa et al.
Digestive diseases and sciences, 52(3), 650-658 (2007-01-27)
The goal of this study was to evaluate the preventive effect of free glutamine versus N-acetyl-L-glutamine, a liquid-stable source of glutamine, on gut damage induced by protein energy malnutrition in pigs. Healthy pigs (n = 6) were fed a liquid
M C Gouttebel et al.
JPEN. Journal of parenteral and enteral nutrition, 16(2), 117-121 (1992-03-01)
Glutamine is a nonessential neutral amino acid that is widely consumed by the intestinal tract in catabolic states. We have followed up the plasma amino acid profile after extensive small-bowel resection in dogs receiving total parenteral nutrition (TPN) with or
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