50847

Gramicidin C from Bacillus brevis

~90% (HPLC)

• CAS Number: 9062-61-7
• MDL number: MFCD00466945
• UNSPSC Code: 51283112
• NACRES: NA.85

Properties

• biological source: Bacillus brevis
• Quality Level: 100
• Assay: ~90% (HPLC)
• form: powder
• impurities: ≤5% water
• color: white to off-white
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria
• Mode of action: cell membrane | interferes; enzyme | inhibits
• storage temp.: 2-8°C
• SMILES string: CC(C)C[C@@H]1NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(=O)[C@@H]4CCCN4C(=O)[C@@H](Cc5ccccc5)NC1=O)C(C)C)C(C)C
• InChI key: IUAYMJGZBVDSGL-JYFSIOBESA-N

Description

General description

Chemical structure: peptide

Application

Gramicidin is a naturally occuring polypeptide antibiotic. It functions as a transmembrane ion channel and is used for studies on phospholipid bilayer membrane fluidity measured by lateral diffusion.

Biochem/physiol Actions

Gramicidin′s bactericidal activity is a result of increasing the permeability of the bacterial cell membrane. This allows inorganic monovalent cations to travel through unrestricted which thereby destroys the ion gradient between the cytoplasm and the extracellular environment .

Naturally occuring polypeptide antibiotic with Tyr at position 11; functions as a transmembrane ion channel.

Packaging

10mg

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place. Keep in a dry place.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves