239305

Sodium hypochlorite solution

reagent grade, available chlorine 4.00-4.99 %

• Linear Formula: NaClO
• CAS Number: 7681-52-9
• Molecular Weight: 74.44
• EC Number: 231-668-3
• MDL number: MFCD00011120
• UNSPSC Code: 12352300
• PubChem Substance ID: 329752526
• NACRES: NA.21

Properties

• grade: reagent grade
• Agency: suitable for SM 4500 - NH3
• vapor pressure: 17.5 mmHg ( 20 °C)
• form: liquid
• composition: available chlorine, 4.00-4.99%
• reaction suitability: reagent type: oxidant
• concentration: 4.00-4.99% (chlorine by Na₂S₂O₃, titration)
• density: 1.097 g/mL at 25 °C
• storage temp.: 2-8°C
• SMILES string: [Na+].[O-]Cl
• InChI: 1S/ClO.Na/c1-2;/q-1;+1
• InChI key: SUKJFIGYRHOWBL-UHFFFAOYSA-N

Description

General description

Sodium hypochlorite (NaOCl) is a commonly used reagent in organic synthesis for many oxidation and chlorination reactions.

Application

Sodium hypochlorite solution can be used as an oxidizing agent for the oxidation of:      

• Primary alcohols to aldehydes or carboxylic acids and secondary alcohols to ketones.     
• Aryl aldehydes to the corresponding acids in the presence of a phase-transfer catalyst.      
• Ethers to esters by careful pH control (pH range of 8–9.5),

It can also be used as a reagent in the:      

• Epoxidation of enones and polycyclic arenes.      
• Oxidative degradation reaction      
• N-Chlorination of primary and secondary amines
• Enantioselective epoxidation of α, β-unsaturated ketones      
• Asymmetric dihydroxylation of olefins in the presence of an osmium catalyst      
• Chlorination of allylic carbons in the presence of CeCl₃

Features and Benefits

• Readily available reagent      
• Easily handled oxidizing agent      
• No phase-transfer catalyst is necessary for the oxidation of substrates in the pH range 10–11     
• Simplified waste disposal and lower toxicity

Disclaimer

“The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.”

Safety Information

• Pictograms: GHS05,GHS09
• Signal Word: Danger
• Hazard Statements: H315,H318,H410
• Precautionary Statements: P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable