PHR1238

Ergocalciferol (Vitamin D2)

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Ergocalciferol, Calciferol, Ercalciol, Ergosterol irradiated, Irradiated ergosterol, Vitamin D₂
• Empirical Formula (Hill Notation): C₂₈H₄₄O
• CAS Number: 50-14-6
• Molecular Weight: 396.65
• Beilstein: 1916682
• EC Number: 200-014-9
• MDL number: MFCD00166988
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823243
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• Agency: traceable to BP 788; traceable to Ph. Eur. E0900000; traceable to USP 1239005
• API family: ergocalciferol
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• mp: 114-118 °C (lit.)
• application(s): clinical testing
• format: neat
• storage temp.: -10 to -25°C
• SMILES string: CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C
• InChI: 1S/C28H44O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h9-10,12-13,19-20,22,25-27,29H,4,7-8,11,14-18H2,1-3,5-6H3/b10-9+,23-12+,24-13-/t20-,22+,25-,26+,27-,28+/m0/s1
• InChI key: MECHNRXZTMCUDQ-RKHKHRCZSA-N
• Gene Information: human ... VDR(7421)

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Ergocalciferol (Vitamin D2) may be used as a pharmaceutical reference standard for the determination of the analyte in serum samples, cosmetics and pharmaceutical formulations by various chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB7854 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H301 + H311,H330,H372
• Precautionary Statements: P260 - P264 - P280 - P302 + P352 + P312 - P304 + P340 + P310 - P314
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable