Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

76735

Supelco

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride

for GC derivatization, LiChropur™, ≥99.0% (AT)

Synonym(s):

PFBHA·HCl

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
C6F5CH2ONH2·HCl
CAS Number:
57981-02-9
Molecular Weight:
249.57
Beilstein:
4031190
EC Number:
261-057-7
MDL number:
MFCD00012953
UNSPSC Code:
12000000
PubChem Substance ID:
329767306
NACRES:
NA.22

grade

for GC derivatization

Quality Level

100

Assay

≥99.0% (AT)

form

solid

quality

LiChropur™

reaction suitability

reagent type: derivatization reagent
reaction type: Alkylations

technique(s)

gas chromatography (GC): suitable

mp

212-218 °C
227 °C (subl.) (lit.)

solubility

H2O: 5%, clear

SMILES string

Cl.NOCc1c(F)c(F)c(F)c(F)c1F

InChI

1S/C7H4F5NO.ClH/c8-3-2(1-14-13)4(9)6(11)7(12)5(3)10;/h1,13H2;1H

InChI key

HVMVKNXIMUCYJA-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride (PFBHA.HCl) is a derivatizing agent.

Application

PFBHA.HCl has been used for derivatization of metabolites with carbonyl groups followed by analysis via GC-MS. It has also been used in aldehyde derivatization followed by aldehydic hydrolysis using GC/MS.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Sensitive derivatizing agent for electron capture gas chromatographic analysis of carbonyl-containing compounds: keto steroids and carbohydrates

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCM3788
BCCH0583
BCCH6337
BCCG5577
BCCF8143

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Degradation of fluoranthene by Pasteurella sp. IFA and Mycobacterium sp. PYR-1:isolation and identification of metabolites.
Sepic E, Bricelj M, Leskovsek H.
Journal of Applied Microbiology, 85(4), 746-754 null
Plasmalogen degradation by oxidative stress: production and disappearance of specific fatty aldehydes and fatty alpha-hydroxyaldehydes.
Stadelmann-Ingrand S
Free Radical Biology & Medicine, 31(10), 1263-1271 (2001)
Y W Lin et al.
Applied occupational and environmental hygiene, 15(11), 855-862 (2000-11-04)
Ketones are the major positive interferences for an aldehyde dynamic air sampler that consists of 200-mg 20 percent (w/w) O-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine hydrochloride (PFBHA) on Tenax TA contained in a Pyrex tube 7-mm OD, 5-mm ID, and 70-mm in length, that utilizes
S Friedfeld et al.
Geophysical research letters, 27(14), 2093-2096 (2002-01-05)
A one-week in situ intercomparison campaign was completed on the Rice University campus for measuring HCHO using three different techniques, including a novel optical sensor based on difference frequency generation (DFG) operating at room temperature. Two chemical derivatization methods, 2,4-dinitrophenylhydrazine
S Strassnig et al.
Journal of chromatography. A, 891(2), 267-273 (2000-10-24)
A method for the determination of carbonyl compounds, either directly from gaseous phase or following a volatilization from liquid or solid samples after trapping on Tenax TA is presented. Following solvent desorption, the carbonyls are derivatized using O-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine. The reaction
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service