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36186

Supelco

Paraoxon-ethyl

PESTANAL®, analytical standard

Synonym(s):

O,O-Diethyl O-(4-nitrophenyl) phosphate, Diethyl p-nitrophenyl phosphate, Paraoxon, Paraoxon-ethyl

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About This Item

Linear Formula:
O2NC6H4OP(O)(OC2H5)2
CAS Number:
Molecular Weight:
275.20
Beilstein:
1915526
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.51 (lit.)

density

1.274 g/mL at 25 °C (lit.)

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O

InChI

1S/C10H14NO6P/c1-3-15-18(14,16-4-2)17-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3

InChI key

WYMSBXTXOHUIGT-UHFFFAOYSA-N

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General description

Paraoxon-ethyl is an organophosphate pesticide and an inhibitor of acetylcholinesterase. It can undergo degradation by using titania nanoparticles, which are immobilized on glass or quartz substrates.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Potent irreversible acetylcholinesterase inhibitor

Recommended products

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Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbonesEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Photocatalytic degradation of paraoxon-ethyl in aqueous solution using titania nanoparticulate film
Prasad.K.G, et al.
Thin Solid Films, 520(17), 5597-5601 (2012)
Improvement of acetylcholinesterase-based assay for organophosphates in way of identification by reactivators
Pohanka M, et al.
Talanta, 77(1), 451-454 (2008)
Francesca Cavalieri et al.
ACS applied materials & interfaces, 5(2), 464-471 (2012-12-26)
Air-filled lysozyme microbubbles (LSMBs) were engineered as a support for the immobilization of gold nanoparticles and an enzyme, alkaline phosphatase, in order to develop micro-antimicrobial and biosensing devices. Gold nanoparticles immobilized on LSMBs significantly improved the antimicrobial efficacy of the
Krystle L Yozzo et al.
Aquatic toxicology (Amsterdam, Netherlands), 126, 346-354 (2012-10-11)
Using paraoxon as a reference acetylcholinesterase (AChE) inhibitor, the objective of this study was to develop an adverse outcome pathway (AOP) that provided quantitative linkages across levels of biological organization during zebrafish embryogenesis. Within normal zebrafish embryos, we first demonstrated
Guanglei Fu et al.
Talanta, 103, 110-115 (2012-12-04)
Highly sensitive colorimetric detection of organophosphate pesticides (OPs) was developed using Cu (I)-catalyzed click chemistry as the colorimetric signal amplification process between the acetylcholine esterase-acetylthiocholine system (AChE-ATCl) and azide- terminal alkyne-functionalized Au NPs as the colorimetric probe. It was demonstrated

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