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grade
for microscopy
Quality Level
application(s)
environmental
format
neat
InChI
1S/C16H19N5O4S/c1-4-20(7-8-25-12(3)22)13-5-6-14(11(2)9-13)18-19-16-17-10-15(26-16)21(23)24/h5-6,9-10H,4,7-8H2,1-3H3
InChI key
HMAJVAFLGGPIPN-UHFFFAOYSA-N
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General description
Disperse Blue (DB) 124 is a strong clothing dye sensitizer. It is also an important textile dye allergen.
Application
DB 124 was used during testing the sensitizing potential of the dye using loose-fit coculture-based sensitization assay (LCSA).
Other Notes
Dye standard for the assay of allergy-releasing dyes in textiles
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral - Skin Sens. 1
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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B M Hausen
Contact dermatitis, 28(3), 169-173 (1993-03-01)
9 cases of allergic contact dermatitis due to black "velvet" fabrics, mostly leggings, are reported. In all cases, the 2 disperse dyes Blue 106 and 124 were shown to be the responsible contact sensitizers. Preparation of a chloroform extract and
Clothing dye dermatitis masquerading as (coexisting) mimosa allergy.
J D Guin et al.
Contact dermatitis, 40(1), 45-45 (1999-02-03)
Z Caliskaner et al.
Human & experimental toxicology, 31(1), 101-103 (2011-10-27)
Disperse blue (DB) 106 and DB 124 are the most frequent fabric dye allergens inducing textile dermatitis, but contact allergy to them may easily undiagnosed because the clinical picture usually needs high index of suspicion. We present the case of
Nonpruritic contact dermatitis from disperse blue dyes.
Aaron Wong et al.
Dermatitis : contact, atopic, occupational, drug, 22(5), 278-280 (2012-06-02)
P Komericki et al.
Journal of the American Academy of Dermatology, 45(3), 456-458 (2001-08-21)
The diagnosis of purpura pigmentosa progressiva in a female patient had to be changed to purpuric contact dermatitis after patch testing with textile dyes. A modified patch test performed in the area in which most of her skin lesions were
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