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Key Documents

T45802

Sigma-Aldrich

2,4,6-Triaminopyrimidine

97%

Synonym(s):

2,4,6-Pyrimidinetriamine

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About This Item

Empirical Formula (Hill Notation):
C4H7N5
CAS Number:
Molecular Weight:
125.13
Beilstein:
118448
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

97%

mp

249-251 °C (lit.)

SMILES string

Nc1cc(N)nc(N)n1

InChI

1S/C4H7N5/c5-2-1-3(6)9-4(7)8-2/h1H,(H6,5,6,7,8,9)

InChI key

JTTIOYHBNXDJOD-UHFFFAOYSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Chris M Wood et al.
The Journal of experimental biology, 215(Pt 3), 508-517 (2012-01-17)
Paracellular permeability and absorptive water flux across the intestine of the euryhaline killifish were investigated using in vitro gut sac preparations from seawater- and freshwater-acclimated animals. The permeability of polyethylene glycol (PEG), a well-established paracellular probe, was measured using trace
The effect of electrical gradients on current fluctuations and impedance recorded from Necturus gallbladder.
H Gögelein et al.
The Journal of membrane biology, 60(3), 199-209 (1981-01-01)
W L Armarego et al.
The Biochemical journal, 211(2), 357-361 (1983-05-01)
The Km and kcat. values for [6,6,7,7-2H]7,8(6H)-dihydropterin and 2,6-diamino-5-iminopyrimidin-4-one were determined for dihydropteridine reductase (EC 1.6.99.10) from two sources. The parameters of the pterin are of the same order as those of the most effective substrates of dihydropteridine reductase. The
R Soni et al.
Journal of the National Cancer Institute, 93(6), 436-446 (2001-03-22)
Cyclin-dependent kinase 4 (Cdk4) represents a prime target for the treatment of cancer because most human cancers are characterized by overexpression of its activating partner cyclin D1, loss of the natural Cdk4-specific inhibitor p16, or mutation(s) in Cdk4's catalytic subunit.
P Y Wong
Experientia, 36(5), 570-571 (1980-05-15)
Intracellular potentials in the cells from 17.5-day old rat visceral yolk sacs were measured by a glass microelectrode. When penetrated from the maternal side, the cells have potentials of about 50.2 +/- 1.9 mV (inside negative) which were reduced by

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