Skip to Content
Merck
All Photos(3)

Key Documents

View All Documentation

T15601

Sigma-Aldrich

Tetrahydrothiophene

99%

Synonym(s):

THT, Tetramethylene sulfide, Thiolane, Thiophane

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Empirical Formula (Hill Notation):
C4H8S
CAS Number:
110-01-0
Molecular Weight:
88.17
Beilstein:
102392
EC Number:
203-728-9
MDL number:
MFCD00005476
UNSPSC Code:
12352100
PubChem Substance ID:
24899981
NACRES:
NA.22

vapor pressure

18 mmHg ( 25 °C)

Quality Level

100

Assay

99%

refractive index

n20/D 1.504 (lit.)

bp

119 °C (lit.)

mp

−96 °C (lit.)

density

1 g/mL at 25 °C (lit.)

SMILES string

C1CCSC1

InChI

1S/C4H8S/c1-2-4-5-3-1/h1-4H2

InChI key

RAOIDOHSFRTOEL-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Tetrahydrothiophene can be used as a reagent for the synthesis of various epoxides and their derivatives. It can be used as a catalyst for the synthesis of benzo[n.1.0]bicycloalkanes.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

55.4 °F - closed cup

Flash Point(C)

13 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

Sulfolane 99%

Sigma-Aldrich

T22209

Sulfolane

A new protocol for the in situ generation of aromatic, heteroaromatic, and unsaturated diazo compounds and its application in catalytic and asymmetric epoxidation of carbonyl compounds. Extensive studies to map out scope and limitations, and rationalization of diastereo-and enantioselectivities.
Aggarwal VK, et al.
Journal of the American Chemical Society, 125(36), 10926-10940 (2003)
Tetrahydrothiophene-catalyzed synthesis of benzo [n.1.0] bicycloalkanes.
Ye LW, et al.
The Journal of Organic Chemistry, 72(4), 1335-1340 (2007)
Catalytic asymmetric synthesis of epoxides from aldehydes using sulfur ylides with in situ generation of diazocompounds.
Aggarwal VK, et al.
Angewandte Chemie (International Edition in English), 40(8), 1430-1433 (2001)
Sanat Ghosh et al.
Physical chemistry chemical physics : PCCP, 22(31), 17482-17493 (2020-06-13)
This is a tale of a pair of a hydrogen bond donor and acceptor, namely the CH donor and sulphur acceptor, neither of which is a conventional hydrogen bond participant. Sulfur (S), being less electronegative (2.58) compared to its first
W S Cain et al.
American Industrial Hygiene Association journal, 46(3), 115-126 (1985-03-01)
LP-gas derives warning properties from the odorants ethyl mercaptan or thiophane. Laboratory tests have implied that the average person has the ability to smell the odors before leaking LP-gas reaches one-fifth its lower limit of flammability. Generally, however, laboratory tests
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service