Skip to Content
Merck
All Photos(3)

Key Documents

View All Documentation

P62402

Sigma-Aldrich

4-Pyridinecarboxaldehyde

97%

Synonym(s):

Isonicotinaldehyde

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Empirical Formula (Hill Notation):
C6H5NO
CAS Number:
872-85-5
Molecular Weight:
107.11
Beilstein:
105342
EC Number:
212-832-3
MDL number:
MFCD00006425
UNSPSC Code:
12352100
PubChem Substance ID:
24898732
NACRES:
NA.22

Assay

97%

refractive index

n20/D 1.544 (lit.)

bp

71-73 °C/10 mmHg (lit.)

density

1.137 g/mL at 20 °C (lit.)

storage temp.

2-8°C

SMILES string

[H]C(=O)c1ccncc1

InChI

1S/C6H5NO/c8-5-6-1-3-7-4-2-6/h1-5H

InChI key

BGUWFUQJCDRPTL-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

4-Pyridinecarboxaldehyde is a heterocyclic building block used to prepare Schiff bases via a Korich-type reaction.

Application

4-Pyridinecarboxaldehyde can be used for the synthesis of:
  • ʅ,β-Unsaturated amides by coupling with N,N-disubstituted formamides.
  • meso-Substituted A3-corroles.
  • N-(4-pyridylmethyl)-L-valine as a ligand to construct zinc metal–organic frameworks (Zn-MOFs).
  • 4′-Pyridyl terpyridines, with potential application as anticancer and antimicrobial agents.
  • 4-pyridinecarboxaldehyde thiosemicarbazone, as a corrosion inhibitor for mild steel.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H314,H317,H412

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

172.0 °F

Flash Point(C)

77.8 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A combined computational/experimental study on HSA binding of two water-soluble Schiff base ligands derived from pyridine derivative and ethylendiamine.
Hajar Molaee et al.
Journal of biomolecular structure & dynamics, 37(3), 641-648 (2018-02-03)
Cross coupling of acyl and aminyl radicals: Direct synthesis of amides catalyzed by Bu4NI with TBHP as an oxidant.
Liu Z, et al.
Angewandte Chemie (International Edition in English), 51(13), 3231-3235 (2012)
Experimental and theoretical evaluation of two pyridinecarboxaldehyde thiosemicarbazone compounds as corrosion inhibitors for mild steel in hydrochloric acid solution.
Xu B, et al.
Corrosion Science, 78(9), 260-268 (2014)
Poly (ethyleneglycol)(PEG): a versatile reaction medium in gaining access to 4?-(pyridyl)-terpyridines.
Smith CB, et al.
Green Chemistry, 7(9), 650-654 (2005)
Efficient synthesis of meso-substituted corroles in a H2O- MeOH mixture.
Koszarna B and Gryko DT
The Journal of Organic Chemistry, 71(10), 3707-3717 (2006)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service