D188700

N,N′-Dimethylthiourea

99%

• Synonym(s): 1,3-Dimethyl-2-thiourea, 1,3-Dimethylisothiourea, Dimethylthiocarbamide
• Linear Formula: CH₃NHCSNHCH₃
• CAS Number: 534-13-4
• Molecular Weight: 104.17
• Beilstein: 605454
• EC Number: 208-588-2
• MDL number: MFCD00004923
• UNSPSC Code: 12352100
• PubChem Substance ID: 24893565
• NACRES: NA.22

Properties

• Assay: 99%
• form: crystals
• SMILES string: CNC(=S)NC
• InChI: 1S/C3H8N2S/c1-4-3(6)5-2/h1-2H3,(H2,4,5,6)
• InChI key: VLCDUOXHFNUCKK-UHFFFAOYSA-N

Description

General description

N,N′-Dimethylthiourea, also known as 1,3-Dimethylisothiourea, is commonly used in organic reactions to synthesize N-containing compounds such as N-acyl-substituted 1,1-diaminoethylenes, amidines, ureas, and thioureas. It also acts as a nucleophilic catalyst in the bromination of alcohols using N-bromosuccinimide (NBS), during the conversion to the corresponding bromides.

Application

• Pharmaceutical Analysis: Mao et al. developed an itaconic acid-based organic-polymer monolithic column for hydrophilic capillary electrochromatography, which was used in pharmaceutical analysis. N,N′-Dimethylthiourea could be utilized to improve the column′s performance by acting as a potential organic modifier to enhance the separation processes (Mao et al., 2024).
• Agricultural Research: Li et al. examined the effect of the reactive oxygen scavenger N,N′-Dimethylthiourea on seed germination and radicle elongation of maize. This research could help in understanding how this chemical can be used to influence plant growth under stress conditions, potentially improving agricultural productivity (Li et al., 2023).

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H317
• Precautionary Statements: P280
• Hazard Classifications: Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves