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C8527

Sigma-Aldrich

Chlorhexidine dihydrochloride

≥98%

Synonym(s):

1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane; 1,1′-Hexamethylenebis(5-[p-chlorophenyl]biguanide), Lisium

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About This Item

Empirical Formula (Hill Notation):
C22H30Cl2N10 · 2HCl
CAS Number:
3697-42-5
Molecular Weight:
578.37
EC Number:
223-026-6
MDL number:
MFCD00068998
UNSPSC Code:
12352100
PubChem Substance ID:
57654049
NACRES:
NA.22

Quality Level

100

Assay

≥98%

form

powder

storage temp.

2-8°C

SMILES string

Cl.Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1

InChI

1S/C22H30Cl2N10.2ClH/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;;/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*1H

InChI key

WJLVQTJZDCGNJN-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Steven P Engebretson et al.
JAMA, 310(23), 2523-2532 (2013-12-19)
Chronic periodontitis, a destructive inflammatory disorder of the supporting structures of the teeth, is prevalent in patients with diabetes. Limited evidence suggests that periodontal therapy may improve glycemic control. To determine if nonsurgical periodontal treatment reduces levels of glycated hemoglobin
Maristela Dutra-Correa et al.
The journal of adhesive dentistry, 15(3), 287-292 (2013-04-06)
This study tested the hypothesis that 2% chlorhexidine (CHX) does not affect the 18-month clinical performance of two dentin adhesives, XP Bond (XPB) and XENO V (XEN). A total of 120 noncarious cervical lesions (NCCL) were selected and assigned to
Karl A Hassan et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(50), 20254-20259 (2013-11-28)
Chlorhexidine is widely used as an antiseptic or disinfectant in both hospital and community settings. A number of bacterial species display resistance to this membrane-active biocide. We examined the transcriptomic response of a representative nosocomial human pathogen, Acinetobacter baumannii, to
C M Martín-Navarro et al.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 251(9), 2111-2117 (2013-05-21)
Acanthamoeba is an opportunistic pathogen which is the causal agent of a sight-threatening ulceration of the cornea known as "Acanthamoeba keratitis" (AK) and, more rarely, an infection of the central nervous system called "granulomatous amoebic encephalitis" (GAE). The symptoms of
Sissel Skovgaard et al.
The Journal of antimicrobial chemotherapy, 68(10), 2226-2233 (2013-06-07)
Chlorhexidine is used as a disinfectant to prevent surgical infections. Recently, studies have indicated that chlorhexidine usage has selected methicillin-resistant Staphylococcus aureus strains that are tolerant to chlorhexidine and that this may be related to the presence of the qacA/B-encoded
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