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492949

Sigma-Aldrich

L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d10

98 atom % D

Synonym(s):

L-Leucine-C-d10, L-Leucine-d10

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About This Item

Linear Formula:
(CD3)2CDCD2CD(NH2)CO2H
CAS Number:
106972-44-5
Molecular Weight:
141.23
MDL number:
MFCD01321412
UNSPSC Code:
12352209
PubChem Substance ID:
24872790
NACRES:
NA.12

isotopic purity

98 atom % D

Quality Level

200

Assay

99% (CP)

form

solid

optical activity

[α]25/D +14.5°, c = 2 in 5 M HCl

mp

>300 °C (lit.)

mass shift

M+10

SMILES string

[2H]C([2H])([2H])C([2H])(C([2H])([2H])[2H])C([2H])([2H])[C@]([2H])(N)C(O)=O

InChI

1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1/i1D3,2D3,3D2,4D,5D

InChI key

ROHFNLRQFUQHCH-ZWFPVXGPSA-N

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Haiyan Liu et al.
Molecular nutrition & food research, 59(11), 2107-2118 (2015-08-13)
The objective was to investigate the metabolome changes in female rats gavaged with partially purified cranberry procyanidins (PPCP) using (1) H NMR and UHPLC-Q-Orbitrap-HRMS metabolomics approaches, and to identify the contributing metabolites. Twenty-four female Sprague-Dawley rats were randomly separated into
Haiyan Liu et al.
Food & function, 11(3), 2466-2476 (2020-03-07)
The objectives of this research were to investigate urinary metabolome modifications and discover potential intake biomarkers in young women after cranberry juice consumption. Fifteen female college students were given either cranberry juice or apple juice for three days using a
Shaomin Zhao et al.
Molecular nutrition & food research, 64(11), e1901242-e1901242 (2020-04-14)
Methods to verify cranberry juice consumption are lacking. Predictive multivariate models built upon validated biomarkers may help to verify human consumption of a food using a nutrimetabolomics approach. A 21-day double-blinded, randomized, placebo-controlled, cross-over study was conducted among healthy young
Alberto Valdés et al.
Scientific reports, 11(1), 5058-5058 (2021-03-05)
Diabetic nephropathy (DN) is the leading cause of chronic kidney disease. Although hyperglycaemia has been determined as the most important risk factor, hypoxia also plays a relevant role in the development of this disease. In this work, a comprehensive metabolomic
Mohamad-Reza Aghanoori et al.
Molecular metabolism, 20, 149-165 (2018-12-14)
Diabetic sensorimotor polyneuropathy (DSPN) affects approximately half of diabetic patients leading to significant morbidity. There is impaired neurotrophic growth factor signaling, AMP-activated protein kinase (AMPK) activity and mitochondrial function in dorsal root ganglia (DRG) of animal models of type 1

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