47349

Fmoc-Arg(Pbf)-OH

≥98.0% (HPLC)

• Synonym(s): N_α-Fmoc-N_ω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine, N_α-Fmoc-N_ω-Pbf-L-arginine
• Empirical Formula (Hill Notation): C₃₄H₄₀N₄O₇S
• CAS Number: 154445-77-9
• Molecular Weight: 648.77
• Beilstein: 8302671
• MDL number: MFCD00235804
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57650929
• NACRES: NA.26

Properties

• Assay: ≥98.0% (HPLC)
• form: powder or crystals
• optical activity: [α]/D -5.5±1.0°, c = 1 in DMF
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• application(s): peptide synthesis
• functional group: Fmoc
• storage temp.: −20°C
• SMILES string: Cc1c(C)c(c(C)c2CC(C)(C)Oc12)S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)OCC3c4ccccc4-c5ccccc35)C(O)=O
• InChI: 1S/C34H40N4O7S/c1-19-20(2)30(21(3)26-17-34(4,5)45-29(19)26)46(42,43)38-32(35)36-16-10-15-28(31(39)40)37-33(41)44-18-27-24-13-8-6-11-22(24)23-12-7-9-14-25(23)27/h6-9,11-14,27-28H,10,15-18H2,1-5H3,(H,37,41)(H,39,40)(H3,35,36,38)/t28-/m0/s1
• InChI key: HNICLNKVURBTKV-NDEPHWFRSA-N

Description

General description

Fmoc-Arg(Pbf)-OH is used as a building block in peptide synthesis, providing protection to specific functional groups while allowing for efficient peptide bond formation.

Application

Fmoc-Arg(Pbf)-OH is a Fmoc-protected amino acid derivative that can be used to create arginine-containing peptides. The 2,2,4,6,7-pentamethyIdlhydrobenzofuran-5-sulfonyl group (Pbf) can be easily cleaved by trifluoroacetic acid (TFA).

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves