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411779

Sigma-Aldrich

N-tert-Butylacrylamide

97%

Synonym(s):

N -(1,1-Dimethylethyl)-2-propenamide, N -t -Butylacrylamide

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About This Item

Linear Formula:
CH2=CHCONHC(CH3)3
CAS Number:
Molecular Weight:
127.18
Beilstein:
1742331
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

Assay

97%

form

solid

mp

126-129 °C (lit.)

SMILES string

CC(C)(C)NC(=O)C=C

InChI

1S/C7H13NO/c1-5-6(9)8-7(2,3)4/h5H,1H2,2-4H3,(H,8,9)

InChI key

XFHJDMUEHUHAJW-UHFFFAOYSA-N

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General description

N-tert-Butylacrylamide (nTBA) belongs to the class of hydrophobic acrylamides which can be synthesized by Ritter reaction and optimized by using N-tert-butyl acetate and acetic acid.

Application

nTBA is temperature sensitive monomers that can be potentially used in drug delivery systems, dewatering of proteins, and immobilization of cells. It can be used in the preparation of poly(nTBA) based copolymeric hydrogels for bovin serum albumin.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hossein Hosseinzadeh et al.
International journal of biological macromolecules, 113, 859-868 (2018-03-11)
In the present work, a novel magnetic chitosan/graphene oxide nanocomposite (MCGON) was synthesized for the removal of Cu2+ from aqueous solutions. The adsorbent was composed of graphene oxide (GO) modified by ethylenediamine (ED), Fe3O4 nanoparticles and chitosan-g-poly(acrylic acid-co-2-acrylamido-2-methylpropane sulfonic acid)
Yuma Nagasawa et al.
Polymers, 11(6) (2019-06-13)
The chemisorption process with amines is the major separation and recovery method of CO2 because of its high processing capacity and simplicity. However, large energy consumption for the desorption of CO2 is also associated with the process. To develop a
Lucia Cenci et al.
Talanta, 178, 772-779 (2017-11-16)
Nanosized Molecularly Imprinted Polymers (nanoMIPs) are designed artificial nanoreceptors with a predetermined selectivity and specificity for a given analyte, lately proposed as a replacement to antibodies in immunoassays. The nanoMIP-plate preparation based on nanoparticle adsorption was studied with the aim
An efficient and scalable ritter reaction for the synthesis of tert-butyl amides
Baum JC, et al.
The Journal of Organic Chemistry, 74(5), 2207-2209 (2009)
Graft copolymerization onto starch-I. Synthesis and optimization of starch grafted with N-tert-butylacrylamide copolymer and its hydrogels
Fares MM, et al.
Journal of Polymer Research, 10(2), 119-125 (2003)

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