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Key Documents

298417

Sigma-Aldrich

(R)-(−)-Leucinol

98%

Synonym(s):

(R)-2-Amino-4-methyl-1-pentanol, D-Leucinol

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About This Item

Linear Formula:
(CH3)2CHCH2CH(NH2)CH2OH
CAS Number:
Molecular Weight:
117.19
Beilstein:
1719241
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

optical activity

[α]20/D −4°, c = 9 in ethanol

reaction suitability

reaction type: solution phase peptide synthesis

refractive index

n20/D 1.4496 (lit.)

bp

198-200 °C/768 mmHg (lit.)

density

0.917 g/mL at 25 °C (lit.)

application(s)

peptide synthesis

SMILES string

CC(C)C[C@@H](N)CO

InChI

1S/C6H15NO/c1-5(2)3-6(7)4-8/h5-6,8H,3-4,7H2,1-2H3/t6-/m1/s1

InChI key

VPSSPAXIFBTOHY-ZCFIWIBFSA-N

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

194.0 °F - closed cup

Flash Point(C)

90 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Klaus Ringsborg Westphal et al.
Toxins, 11(5) (2019-05-19)
Fungal non-ribosomal peptide synthetase (NRPS) clusters are spread across the chromosomes, where several modifying enzyme-encoding genes typically flank one NRPS. However, a recent study showed that the octapeptide fusaoctaxin A is tandemly synthesized by two NRPSs in Fusarium graminearum. Here
Griet Van Zeebroeck et al.
Nature chemical biology, 5(1), 45-52 (2008-12-09)
Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting transceptors is unknown. We have screened 319 amino acid analogs to identify compounds that act on Gap1

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